Chemical composition, antibacterial screening and cytotoxic activity of Chiliadenus antiatlanticus (Asteraceae) essential oil
WILEY-V C H VERLAG GMBH, 2021
Online
academicJournal
Zugriff:
The chemical composition and in vitro antibacterial and cytotoxic activities of the essential oil (EO) of Chiliadenus antiatlanticus (Emb. & Maire) Gomiz, an asteraceous species endemic to the southwest of Morocco, were investigated. The EO yield was 1.07 +/- 0.28 %, twenty-seven metabolites were identified representing more than 96.4 % of the total composition. Camphor (35.7 %) and derivatives, borneol (4.9 %) and camphene (4.2 %) together with intermedeol (19.9 %), alpha-pinene (15.5 %) and (E)-pinocarveol (4.1 %) were the major constituents. An antibacterial activity was noticed against 24 strains (all Gram-positive) out of 71 at MICs values=100 mu g/mL. The EO also showed significant toxicity towards liver HepG2 (55.8 % of cell viability) and melanoma B16 4A5 (41.6 % of cell viability) tumor cell lines at 100 mu g/mL.
University of Paris; Ibn Zohr University; Fundacao para a Ciencia e a Tecnologia (FCT)Portuguese Foundation for Science and TechnologyEuropean Commission
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Chemical composition, antibacterial screening and cytotoxic activity of Chiliadenus antiatlanticus (Asteraceae) essential oil
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| Autor/in / Beteiligte Person: | El Yaagoubi, Mohamed ; Ortiz, Sergio ; Mechqoq, Hicham ; Cavaleiro, Carlos ; Lecso-Bornet, Marylin ; Rodrigues, Maria Joao ; Custódio, Luísa ; El Mousadik, Abdelhamid ; Grougnet, Raphael ; El Aouad, Noureddine ; Msanda, Fouad ; Kritsanida, Marina ; Sapientia |
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| Veröffentlichung: | WILEY-V C H VERLAG GMBH, 2021 |
| Medientyp: | academicJournal |
| DOI: | 10.1002/cbdv.202100115 |
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