Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas
In: PLoS Medicine, Jg. 4 (2007-10-01), Heft 10, S. 1655-1668
Online
academicJournal
Zugriff:
ABSTRACT Background Mutations in the epidermal growth factor receptor (EGFR) gene are associated with increased sensitivity of lung cancers to kinase inhibitors like erlotinib. Mechanisms of cell death that occur [...]
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Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas
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Autor/in / Beteiligte Person: | Gong, Yixuan ; Somwar, Romel ; Politi, Katerina ; Balak, Marissa ; Chmielecki, Juliann ; Jiang, Xuejun ; Pao, William |
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Zeitschrift: | PLoS Medicine, Jg. 4 (2007-10-01), Heft 10, S. 1655-1668 |
Veröffentlichung: | 2007 |
Medientyp: | academicJournal |
ISSN: | 1549-1277 (print) |
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