N-linked glycosylation of the human ABC transporter ABCG2 on asparagine 596 is not essential for expression, transport activity, or trafficking to the plasma membrane
In: Biochemistry, Jg. 44 (2005-04-12), Heft 14, S. 5420-5429
academicJournal
Zugriff:
Glycosylation being not essential for the transport function and gross conformation of ABCG2, the human ATP-binding cassette half-transporter, was demonstrated. This result along with the fact that the glycosylation deficient protein population appears to be homogenous, suggests that it is possible to generate large quantities of ABCG2 for three-dimensional crystallographic analyses in both mammalian and microbial systems.
Titel: |
N-linked glycosylation of the human ABC transporter ABCG2 on asparagine 596 is not essential for expression, transport activity, or trafficking to the plasma membrane
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Autor/in / Beteiligte Person: | Diop, Ndeye K. ; Hrycyna, Christine A. |
Zeitschrift: | Biochemistry, Jg. 44 (2005-04-12), Heft 14, S. 5420-5429 |
Veröffentlichung: | 2005 |
Medientyp: | academicJournal |
ISSN: | 0006-2960 (print) |
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