Deep brain stimulation with short versus conventional pulse width in Parkinson's disease and essential tremor: A systematic review and meta-analysis
In: Brain Stimulation, Jg. 17 (2024), Heft 1, S. 71-82
Online
academicJournal
Zugriff:
Background: To maximize clinical benefit and minimize stimulation-induced side effects, optimising deep brain stimulation (DBS) parameters is paramount. Recent literature suggests a potential benefit of short pulse width DBS (spDBS; ≤40 μs) over conventional pulse width DBS (cDBS; ≥60 μs) in movement disorders. Objective: To compare therapeutic window (TW), therapeutic and side effects and energy consumption of spDBS and cDBS in movement disorders. Methods: We systematically searched Medline, Embase, Cochrane Library and Web of Science. Appropriate paired analyses were performed. Results: Nine Parkinson's disease (PD) (143 patients), 4 essential tremor (ET) (26 patients) and no dystonia studies were included in the meta-analysis. TW defined as therapeutic amplitude range was larger with spDBS vs. cDBS in PD (standardized mean difference (SMD) = -1.04, p
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Deep brain stimulation with short versus conventional pulse width in Parkinson's disease and essential tremor: A systematic review and meta-analysis
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Autor/in / Beteiligte Person: | Smeets, Sara ; Boogers, Alexandra ; Tine Van Bogaert ; Peeters, Jana ; McLaughlin, Myles ; Nuttin, Bart ; Theys, Tom ; Vandenberghe, Wim ; Philippe De Vloo |
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Zeitschrift: | Brain Stimulation, Jg. 17 (2024), Heft 1, S. 71-82 |
Veröffentlichung: | Elsevier, 2024 |
Medientyp: | academicJournal |
ISSN: | 1935-861X (print) |
DOI: | 10.1016/j.brs.2023.12.013 |
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