Chemical composition and antifungal activity of the essential oil of Varronia schomburgkii (DC.) Borhidi (Cordiaceae) from plants cultivated in French Guiana
In: ISSN: 1041-2905 ; Journal of Essential Oil Research ; https://hal.umontpellier.fr/hal-02163760 ; Journal of Essential Oil Research, 2017, 2017
Online
academicJournal
Zugriff:
International audience ; This study reports for the first time the chemical composition of the essential oil of Varronia schomburgkii (DC.) Borhidi cultivated in French Guiana. This essential oil was examined by a combination of GC/FID and GC-MS techniques and was further tested for antifungal activity against several Candida strains, as well as for anti-leishmanial activity against the reference strain Leishmania guyanensis. A total of 45 components accounting for 93.61% of the total GC/FID chromatogram were identified. The essential oil is dominated by sesquiterpenes and oxygenated sesquiterpenes among which ?-caryophyllene (46.99 ± 0.32%) is the major one. No anti-leishmania activity could be assessed, while a strong antimicrobial activity of this essential oil was evidenced in vitro against a Candida albicans strain by the definition of a MIC value of 250 ?g/mL. V. schomburgkii essential oil might hence be considered in the future for the development of natural antifungal agents.
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Chemical composition and antifungal activity of the essential oil of Varronia schomburgkii (DC.) Borhidi (Cordiaceae) from plants cultivated in French Guiana
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| Autor/in / Beteiligte Person: | Scotto, Camille Inès ; Burger, Pauline ; Khodjet El Khil, Mehdi ; Ginouvès, Marine ; Prévot, Ghislaine ; Blanchet, Denis ; Delprete, Piero G. ; Fernandez, Xavier ; Institut de Chimie de Nice (ICN) ; Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA) ; Ecosystemes Amazoniens et Pathologie Tropicale (EPat) ; Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Guyane (UG) ; Botanique et Modélisation de l'Architecture des Plantes et des Végétations (UMR AMAP) ; Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD France-Sud ) ; Oleaflore ; Conseil Régional de la Guyane ; University of French Guiana ; ANR-10-LABX-0025,CEBA,CEnter of the study of Biodiversity in Amazonia(2010) ; European Project: 31454,FEDER- Presage |
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| Zeitschrift: | ISSN: 1041-2905 ; Journal of Essential Oil Research ; https://hal.umontpellier.fr/hal-02163760 ; Journal of Essential Oil Research, 2017, 2017 |
| Veröffentlichung: | HAL CCSD ; Taylor & Francis, 2017 |
| Medientyp: | academicJournal |
| DOI: | 10.1080/10412905.2017.1278729 |
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