Analysis of the prevalence, risk factors, and clinical characteristics of osteoporosis in patients with essential hypertension
In: BMC Endocrine Disorders, Jg. 22 (2022-06-27)
Online
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Zugriff:
Background The present study investigated the prevalence of osteoporosis (OP) among patients with essential hypertension (EH) in the Changchun community and analysed the correlation between EH and OP. Methods The study included 425 subjects with EH and 425 age- and sex-matched healthy controls. Bone mineral density (BMD) and serum creatinine (CR) levels were measured, and the subjects' current EH and OP statuses were surveyed to analyse the correlation between EH and OP. Results The EH group exhibited lower BMD and a higher rate of having OP than the control group, and this difference was statistically significant (p p p = 0.028, bias η2 = 0.008). Conclusions The prevalence of OP and low BMD were significantly higher among subjects with EH than among healthy controls. Additionally, the findings indicate that age, weight, fracture history, nocturnal urination frequency, depression and anxiety, duration of hypertension and antihypertensive drug use may be correlated to having OP in EH subjects, requiring further studies. Moreover, serum CR levels in subjects with different bone mass profiles were strongly influenced by the presence or absence of EH, and the serum CR levels differed significantly with the interaction of these two factors.
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Analysis of the prevalence, risk factors, and clinical characteristics of osteoporosis in patients with essential hypertension
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Autor/in / Beteiligte Person: | Hai-Long, Wu ; Jie, Yang ; Yu-Chi, Wei ; Jian-Yu, Wang ; Yu-Yan, Jia ; Luan, Li ; Lu, Zhang ; Yan, Lu ; Zong-Jian, Luo ; Xiang-Yang, Leng |
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Zeitschrift: | BMC Endocrine Disorders, Jg. 22 (2022-06-27) |
Veröffentlichung: | Springer Science and Business Media LLC, 2022 |
Medientyp: | unknown |
ISSN: | 1472-6823 (print) |
DOI: | 10.1186/s12902-022-01080-w |
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