Interferon-α induces marked alterations in circulating regulatory T cells, NK cell subsets, and dendritic cells in patients with JAK2V617F-positive essential thrombocythemia and polycythemia vera
In: European journal of haematology, Jg. 97 (2015-09-14), Heft 1
Online
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Zugriff:
Long-term therapy with IFN-α2 is associated with sustained major molecular remissions in JAK2-positive ET and PV. The efficacy of IFN-α2 may be partly mediated by modulation of immune cells, which was investigated in twenty patients with ET (n = 6) and PV (n = 14). The frequency of CD4(+) CD25(+) Foxp3(+) T cells was significantly increased during IFN-α2 treatment in all patients (P
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Interferon-α induces marked alterations in circulating regulatory T cells, NK cell subsets, and dendritic cells in patients with JAK2V617F-positive essential thrombocythemia and polycythemia vera
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Autor/in / Beteiligte Person: | Marie Klinge Brimnes ; Per thor Straten ; Jensen, Morten K. ; Caroline Hasselbalch Riley ; Inge Marie Svane ; Morten Hartvig Hansen ; Kjær, Lasse ; Hans Carl Hasselbalch |
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Zeitschrift: | European journal of haematology, Jg. 97 (2015-09-14), Heft 1 |
Veröffentlichung: | 2015 |
Medientyp: | unknown |
ISSN: | 1600-0609 (print) |
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