Successful thrombolysis in essential thrombocythemia-related acute ischaemic stroke
In: BMJ Case Reports, Jg. 14 (2021-05-01), S. e242925
Online
unknown
Zugriff:
Essential thrombocythemia (ET)-related acute ischaemic stroke (AIS) may account for approximately 0.25%–0.5% of all ischaemic strokes. If left undiagnosed and untreated, patients with ET carry an increased risk of recurrent thrombosis involving major organs including the brain. We report an interesting case of a 67-year-old man, who was successfully thrombolysed for AIS resulting from ET. He presented with sudden onset of left-sided hemiparesis with a left-ventricular clot. His subsequent investigations including positive JAK2 V617F mutation confirmed the diagnosis of ET. He made a significant recovery with thrombolysis, anticoagulation, antiplatelet and hydroxyurea. A fear of post-thrombolytic haemorrhagic complications appears the major reason for the lack of reports of thrombolysis in ET-related AIS. Although the diagnosis of ET was confirmed on subsequent investigations, successful thrombolysis in our case provides preliminary evidence that ET-related AIS cases can undergo successful thrombolysis using tenecteplase. To date, ours is only the second case of ET-related AIS being thrombolysed.
Titel: |
Successful thrombolysis in essential thrombocythemia-related acute ischaemic stroke
|
---|---|
Autor/in / Beteiligte Person: | Mritunjai Kumar Singh ; Kumar, Niraj ; Tiwari, Ashutosh ; Desai, Ishita |
Link: | |
Zeitschrift: | BMJ Case Reports, Jg. 14 (2021-05-01), S. e242925 |
Veröffentlichung: | BMJ, 2021 |
Medientyp: | unknown |
ISSN: | 1757-790X (print) |
DOI: | 10.1136/bcr-2021-242925 |
Schlagwort: |
|
Sonstiges: |
|