Decreased erythrocyte cholesterol/phospholipid ratio in untreated patients with essential hypertension
In: Journal of Internal Medicine, Jg. 232 (1992-09-01), S. 247-251
Online
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Zugriff:
The erythrocyte cholesterol/phospholipid ratio was determined in eight patients with untreated essential hypertension and compared with that of eight age-matched control subjects. The ratio was significantly lower in patients (Wilcoxon's paired rank test; P less than 0.01), and a correlation existed between the ratio and serum cholesterol concentration in patients (r = 0.63) but not in controls (r = 0.02). A reduction in the cholesterol/phospholipid ratio may play a direct role in destabilizing the plasma membrane, which will in turn result in an increase in membrane permeability in essential hypertension.
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Decreased erythrocyte cholesterol/phospholipid ratio in untreated patients with essential hypertension
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Autor/in / Beteiligte Person: | Ronquist, Gunnar ; Frithz, G ; Gunnarsson, K ; Arvidson, G |
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Zeitschrift: | Journal of Internal Medicine, Jg. 232 (1992-09-01), S. 247-251 |
Veröffentlichung: | Wiley, 1992 |
Medientyp: | unknown |
ISSN: | 1365-2796 (print) ; 0954-6820 (print) |
DOI: | 10.1111/j.1365-2796.1992.tb00579.x |
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