Comparison of effects on systolic and diastolic left ventricular function of nebivolol versus atenolol in patients with uncomplicated essential hypertension
In: The American Journal of Cardiology, Jg. 92 (2003-08-01), S. 344-348
Online
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Zugriff:
This was a double-blind, randomized, prospective study comparing the effects of nebivolol and atenolol on systolic diastolic left ventricular function in patients with essential hypertension. A significant difference was seen in stroke volume between these 2 drugs. The blood pressure lowering effect of atenolol was strongly related to cardiac output and heart rate reduction. The blood pressure lowering effect of nebivolol was related to a reduction in peripheral resistance and an increase in stroke volume with preservation of cardiac output. This preservation of cardiac output, together with a reduced peripheral resistance, may be potentially important in treating heart failure.
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Comparison of effects on systolic and diastolic left ventricular function of nebivolol versus atenolol in patients with uncomplicated essential hypertension
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Autor/in / Beteiligte Person: | Sieswerda, Gertjan T. ; Kamp, Otto ; Visser, Cees A. |
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Zeitschrift: | The American Journal of Cardiology, Jg. 92 (2003-08-01), S. 344-348 |
Veröffentlichung: | Elsevier BV, 2003 |
Medientyp: | unknown |
ISSN: | 0002-9149 (print) |
DOI: | 10.1016/s0002-9149(03)00645-3 |
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