Chemical Compositions and Anti-Skin-Ageing Activities of Origanum vulgare L. Essential Oil from Tropical and Mediterranean Region
In: Molecules, Jg. 25 (2020-03-01), Heft 5, p 1101
Online
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Zugriff:
Origanum vulgare L. has been used as a culinary ingredient worldwide. This study revealed the cosmeceutical potential of O. vulgare essential oil as a skin-ageing retardant. The O. vulgare essential oil from a highland area of a tropical country (HO), obtained by hydrodistillation was investigated and compared to a commercial oil from the Mediterranean region (CO). Their chemical compositions were investigated by gas chromatography&ndash
mass spectrometry. Antioxidant activities were investigated by ferric reducing antioxidant power, 1,1-diphenyl-2-picrylhydrazyl, and ferric thiocyanate assay. Anti-skin-ageing activities were determined by means of collagenase, elastase, and hyaluronidase inhibition. Carvacrol was the major component in both oils, but a higher amount was detected in HO (79.5%) than CO (64.6%). HO possessed comparable radical scavenging activity to CO (IC50 = 1.8 ±
0.8 mg/mL) but significantly higher lipid peroxidation inhibition (38.0 ±
0.8%). Carvacrol was remarked as the major compound responsible for the reducing power of both oils. Interestingly, HO possessed significant superior anti-skin-ageing activity than ascorbic acid (P <
0.01), with inhibition against collagenase, elastase, and hyaluronidase of 92.0 ±
9.7%, 53.1 ±
13.3%, and 16.7 ±
0.3%, at the concentration of 67, 25, and 4 µ
g/mL, respectively. Since HO possessed comparable anti-hyaluronidase activity to CO and superior anti-collagenase and anti-elastase (P <
0.01), HO was suggested to be used as a natural skin-ageing retardant in a cosmetic industry.
Titel: |
Chemical Compositions and Anti-Skin-Ageing Activities of Origanum vulgare L. Essential Oil from Tropical and Mediterranean Region
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Autor/in / Beteiligte Person: | Sirithunyalug, Jakkapan ; Laothaweerungsawat, Natnaree ; Chaiyana, Wantida |
Link: | |
Zeitschrift: | Molecules, Jg. 25 (2020-03-01), Heft 5, p 1101 |
Veröffentlichung: | Multidisciplinary Digital Publishing Institute, 2020 |
Medientyp: | unknown |
ISSN: | 1420-3049 (print) |
DOI: | 10.3390/molecules25051101 |
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