Plasma catecholamine responses during a personalized physical stress as a dynamic characterization of essential hypertension
In: Physiology & Behavior, Jg. 49 (1991-04-01), S. 685-690
Online
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Zugriff:
High performance liquid chromatography (HPLC) with electrochemical detection proves to be a reliable method for determination of plasma catecholamines (CA) to assess the possible role of the sympathetic nervous system (SNS) in essential hypertension (EH). The present investigation in a group of 15 normotensive (N) and 13 stable EH patients, homogeneous for age and duration of hypertension, was carried out without treatment in the supine position, up-right position and during a personalized bicycle exercise. Mean blood pressure, mean heart rate, plasma renin activity and plasma aldosterone were also evaluated at the various exertion phases. Norepinephrine (NE) and epinephrine (E) showed a progressive increase in N and in EH patients, reaching the highest values at maximum effort. However, EH patients showed higher E plasma levels than N before maximum effort. Dopamine (DA) reached the highest values in N at maximum effort and in EH patients at recovery time. These findings allow us to foresee the possibility of a better characterization of the SNS role in EH.
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Plasma catecholamine responses during a personalized physical stress as a dynamic characterization of essential hypertension
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Autor/in / Beteiligte Person: | Lucarelli, C. ; Salvati, A. ; Tosti-Croce, C. ; Floridi, A. ; Betto, P. ; Rinaldi, R. ; Sciarra, F. ; Taggi, F. |
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Zeitschrift: | Physiology & Behavior, Jg. 49 (1991-04-01), S. 685-690 |
Veröffentlichung: | Elsevier BV, 1991 |
Medientyp: | unknown |
ISSN: | 0031-9384 (print) |
DOI: | 10.1016/0031-9384(91)90302-5 |
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