Suppression of neutrophil recruitment in mice by geranium essential oil
In: Mediators of Inflammation, Jg. 13 (2004), Heft 1, S. 21-24
Online
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Zugriff:
Background:In aromatherapy, essential oils are used as anti-inflammatory remedies, but experimental studies on their action mechanisms are very limited.Aims of the study:To assess their anti-inflammatory activities, the effects of essential oils on neutrophil recruitment in mice were examinedin vivo.Method:The effect of essential oils on leukocyte and neutrophil recruitment induced 6 h after intraperitoneal injection of casein in mice was examined.Results:Leukocyte recruitment into the peritoneal cavity in mice was suppressed by intraperitoneal injections of geranium, lemongrass and spearmint oils at the dose of 5 μl/mouse, but was not by tea tree oil. This recruitment was inhibited dose-dependently by geranium oil. The suppression of leukocyte recruitment resulted from inhibition of neutrophil accumulation.Conclusion:Some essential oils used as anti-inflammatory remedies suppress neutrophil recruitment into the peritoneal cavity in mice.
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Suppression of neutrophil recruitment in mice by geranium essential oil
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Autor/in / Beteiligte Person: | Yamaguchi, Hideyo ; Maruyama, Naho ; Inouye, Shigeharu ; Abe, Shigeru ; Hayama, Kazumi ; Oshima, Haruyuki |
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Zeitschrift: | Mediators of Inflammation, Jg. 13 (2004), Heft 1, S. 21-24 |
Veröffentlichung: | Hindawi Limited, 2004 |
Medientyp: | unknown |
ISSN: | 1466-1861 (print) ; 0962-9351 (print) |
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