Antifungal and Cytotoxic Activities of Sixty Commercially-Available Essential Oils
In: Molecules, Jg. 23 (2018-06-27), Heft 7, p 1549
Online
unknown
Zugriff:
There is an urgent and unmet need for new antifungal therapies. Global fungal infection rates continue to rise and fungal infections pose increasing burdens on global healthcare systems. Exacerbating the situation, the available antifungal therapeutic arsenal is limited and development of new antifungals has been slow. Current antifungals are known for unwanted side effects including nephrotoxicity and hepatotoxicity. Thus, the need for new antifungals and new antifungal targets is urgent and growing. A collection of 60 commercially-available essential oils has been screened for antifungal activity against Aspergillus niger, Candida albicans, and Cryptococcus neoformans, as well as for cytotoxic activity against MCF-7 and MDA-MB-231 human breast tumor cell lines
the chemical compositions of the essential oils have been determined by gas chromatography-mass spectrometry (GC-MS). Ten essential oils showed remarkable antifungal and cytotoxic activities: Indian, Australian, and Hawaiian sandalwoods
melissa
lemongrass
cilantro
cassia
cinnamon
patchouli
and vetiver.
| Titel: |
Antifungal and Cytotoxic Activities of Sixty Commercially-Available Essential Oils
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| Autor/in / Beteiligte Person: | Jessica L Osier ; Satyal, Prabodh ; Setzer, William N. ; Moriarity, Debra M. ; Emily L Olsen ; Powers, Chelsea N. ; McFeeters, Robert L. ; Carolyn Brianne Brazell |
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| Zeitschrift: | Molecules, Jg. 23 (2018-06-27), Heft 7, p 1549 |
| Veröffentlichung: | Multidisciplinary Digital Publishing Institute, 2018 |
| Medientyp: | unknown |
| ISSN: | 1420-3049 (print) |
| DOI: | 10.3390/molecules23071549 |
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