The effect of essential fatty acid deficiency on the distribution of endogenous cholesterol in the plasma and liver of the rat
In: Archives of Biochemistry and Biophysics, Jg. 52 (1954-09-01), S. 180-185
Online
unknown
Zugriff:
1. 1. When rats were maintained on fat-low diets over a prolonged period, the cholesterol content of the liver and adrenal glands was found to be increased and that of the plasma decreased over that of control rats receiving a diet containing 12.5% of cottonseed oil. 2. 2. The increased cholesterol concentration in the liver of rats on essential fatty acid-low diets was found to be confined almost exclusively to the ester fraction. 3. 3. It is suggested that, in the absence of essential fatty acids, the lowered cholesterol level in the blood and the increased levels in the liver and adrenal glands, may be the result of failure of cholesterol esters containing other than polyunsaturated acids to be available for proper metabolism.
| Titel: |
The effect of essential fatty acid deficiency on the distribution of endogenous cholesterol in the plasma and liver of the rat
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| Autor/in / Beteiligte Person: | Alfin-Slater, Roslyn B. ; Aftergood, Lilla ; Deuel, Harry J. ; Wells, Arthur F. |
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| Zeitschrift: | Archives of Biochemistry and Biophysics, Jg. 52 (1954-09-01), S. 180-185 |
| Veröffentlichung: | Elsevier BV, 1954 |
| Medientyp: | unknown |
| ISSN: | 0003-9861 (print) |
| DOI: | 10.1016/0003-9861(54)90100-9 |
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