Doppler echocardiographic evaluation of the spectrum of left ventricular diastolic dysfunction in essential hypertension
In: American heart journal, Jg. 127 (1994-04-01), Heft 4 Pt 1
Online
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Zugriff:
Left ventricular topography and diastolic and systolic functions were studied in 41 patients with essential hypertension (group 1) and 33 age-matched normal adults (group 2) by Doppler echocardiography. In group 1 54% had LV concentric hypertrophy, 19% had combined concentric hypertrophy and eccentric remodeling, and 27% had concentric remodeling. LV systolic function was within the normal range. In concentric LV remodeling, the EDV was significantly decreased (compared with group 2) (84 +/- 15 vs 130 +/- 38 ml, p0.05), whereas the NPFR was normal (2.89 +/- 0.65 vs 3.22 +/- 0.83 sec-1, p = NS). In concentric hypertrophy, LV end-diastolic and end-systolic volumes were normal, but the NPFR was decreased (2.04 +/- 0.59 sec-1). Patients with concentric hypertrophy and eccentric remodeling had the largest end-diastolic (140 +/- 48 ml) and end-systolic (62 +/- 32 ml) volumes and the lowest NPFR (1.67 +/- 0.69 sec-1). The LVMI inversely correlated with the NPFR (r = -0.89, p0.0001). Thus LV concentric hypertrophy with or without concentric or eccentric remodeling is seen in patients with systemic hypertension. A decrease in peak filling occurs early in the evolution of hypertensive heart disease and is observed even when systolic performance is still normal.
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Doppler echocardiographic evaluation of the spectrum of left ventricular diastolic dysfunction in essential hypertension
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Autor/in / Beteiligte Person: | Iskandrian, Abdulmassih S. ; Ren, Jian-Fang ; Pancholy, Samir ; Segal, Bernard L. ; Mallavarapu, Christopher ; Lighty, George W. |
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Zeitschrift: | American heart journal, Jg. 127 (1994-04-01), Heft 4 Pt 1 |
Veröffentlichung: | 1994 |
Medientyp: | unknown |
ISSN: | 0002-8703 (print) |
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