GM-CSF is not essential for optimal fertility or for weight control
In: Cytokine, Jg. 57 (2011-08-09), Heft 1
Online
unknown
Zugriff:
Independent studies with GM-CSF−/− mice have concluded that GM-CSF is necessary for normal reproductive outcome and for the maintenance of normal weight. In contrast to the literature we report that GM-CSF−/− and wild type (C57Bl/6) mice over a continuous 12 month period had similar litter size and neonatal survival. Likewise, unlike a literature observation, for the two mouse strains both male and female mice had similar weight gain when fed on a normal chow diet and monitored until 30 weeks of age. It is concluded that GM-CSF is not necessary for an optimal fertility outcome or for normal weight maintenance during development.
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GM-CSF is not essential for optimal fertility or for weight control
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Autor/in / Beteiligte Person: | Hamilton, John A. ; Pobjoy, Jarrad ; Cook, Andrew D. ; Davis, Jennifer M. |
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Zeitschrift: | Cytokine, Jg. 57 (2011-08-09), Heft 1 |
Veröffentlichung: | 2011 |
Medientyp: | unknown |
ISSN: | 1096-0023 (print) |
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