Dynamic Adjustments of Parenteral Support in Early Adult Intestinal Failure—Essential Role of Sodium
In: Nutrients, Jg. 12 (2020-11-01), Heft 3426
Online
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Zugriff:
Intestinal failure (IF) requires parenteral support (PS) substituting energy, water, and electrolytes to compensate intestinal losses and replenish deficits. Convalescence, adaptation, and reconstructive surgery facilitate PS reduction. We analyzed the effect of changes of PS on body mass index (BMI) in early adult IF. Energy, volume, and sodium content of PS and BMI were collected at the initial contact (FIRST), the time of maximal PS and BMI (MAX) and the last contact (LAST). Patients were categorized based on functional anatomy: small bowel enterostomy&mdash
group 1, jejuno-colic anastomosis&mdash
group 2. Analysis of variance was used to test the relative impact of changes in energy, volume, or sodium. Total of 50 patients were followed for 596 days. Although energy, volume, and sodium support were already high at FIRST, we increased PS to MAX, which was accompanied by a significant BMI increase. Thereafter PS could be reduced significantly, leading to a small BMI decrease in group 1, but not in group 2. Increased sodium support had a stronger impact on BMI than energy or volume. Total of 13 patients were weaned. Dynamic PS adjustments are required in the early phase of adult IF. Vigorous sodium support acts as an independent factor.
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Dynamic Adjustments of Parenteral Support in Early Adult Intestinal Failure—Essential Role of Sodium
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Autor/in / Beteiligte Person: | Glass, Aenne ; Jacob, Torid ; Lamprecht, Georg ; Reiner, Johannes ; Witte, Maria |
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Zeitschrift: | Nutrients, Jg. 12 (2020-11-01), Heft 3426 |
Veröffentlichung: | MDPI AG, 2020 |
Medientyp: | unknown |
ISSN: | 2072-6643 (print) |
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