Preferential effect of lead exposure during lactation on non-essential fatty acids in maternal organs
In: Lipids, Jg. 40 (2005-10-04), Heft 7
Online
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Zugriff:
This study determined the effects of lead exposure during the lactational period on maternal organ FA compositions in rat dams that were fed either an n−3 adequate (n−3 Adq) or deficient (n−3 Def) diet prior to conception. On giving birth, dams were subdivided into four groups in a 2×2 design with n−3 FA supply and Pb exposure as the dependent variables. Pb acetate (0.2 wt%) was administered in the drinking water from the time they gave birth to weaning 3 wk later. Following weaning, the dams were decapitated. and the liver, plasma, kidney, brain, and retina analyzed for FA composition. The n−3 deficient diets markedly decreased the percentages of total n−3 FA, including docosahexaenoic acid (DHA), and increased total n−6 FA including both arachidonic (AA) and n−6 docosapentaenoic acids in all tissues (P
Titel: |
Preferential effect of lead exposure during lactation on non-essential fatty acids in maternal organs
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Autor/in / Beteiligte Person: | Doherty, John D. ; Lim, Sun-Young ; Loewke, James ; Salem, Norman |
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Zeitschrift: | Lipids, Jg. 40 (2005-10-04), Heft 7 |
Veröffentlichung: | 2005 |
Medientyp: | unknown |
ISSN: | 0024-4201 (print) |
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