The N-terminal tail of C. elegans CENP-A interacts with KNL-2 and is essential for centromeric chromatin assembly
In: Molecular Biology of the Cell, Jg. 32 (2021-06-01), S. 1193-1201
Online
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Zugriff:
Caenorhabditis elegans builds centromeres using the histone H3 variant CENP-A but lacks a CENP-A-specific chaperone. This article shows that the extended N-terminal tail of C. elegans CENP-A, which interacts with the conserved loading factor KNL-2 and is essential for loading, provides at least part of the function of the dedicated chaperone.
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The N-terminal tail of C. elegans CENP-A interacts with KNL-2 and is essential for centromeric chromatin assembly
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Autor/in / Beteiligte Person: | Lara-Gonzalez, Pablo ; Christian O. De Groot ; Shiau, Andrew K. ; Desai, Arshad ; Houston, Jack ; Monen, Joost ; Gerson-Gurwitz, Adina ; Oegema, Karen ; Davis, Bethany |
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Zeitschrift: | Molecular Biology of the Cell, Jg. 32 (2021-06-01), S. 1193-1201 |
Veröffentlichung: | American Society for Cell Biology (ASCB), 2021 |
Medientyp: | unknown |
ISSN: | 1939-4586 (print) ; 1059-1524 (print) |
DOI: | 10.1091/mbc.e20-12-0798 |
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