Composition of Essential Oil from Tagetes minuta and its Cytotoxic, Antioxidant and Antimicrobial Activities
In: Natural Product Communications, Jg. 9 (2014-02-01), S. 1934578X1400900
Online
unknown
Zugriff:
The essential oil from the leaves of Tagetes minuta L., growing wild in Yemen, was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. A total of 28 compounds were identified representing 74.2% of total oil composition. Major components of the essential oil were ( Z)-ocimenone (15.9%), ( E)-ocimenone (34.8%), ( Z)-β-ocimene (8.3%), limonene (2.3%), ( Z)-tagetone (1.8%), dihydrotagetone (1.4%) and an unidentified dimethylvinylketone derivative (20.6%). The oil showed moderate cytotoxic activity against MCF-7 breast tumor cells, with an IC50 of 54.7 ± 6.2 μg/mL. In the DPPH radical scavenging assay, T. minuta oil showed potent antiradical activity with an IC50 value of 36 μg/mL. Antimicrobial activity was also investigated on several microorganisms, and the essential oil exhibited high activity against methicillin-resistant Staphylococcus aureus (MRSA) with an inhibition zone of 23 mm. It also exhibited remarkable antifungal activity against Candida albicans with an inhibition zone of 26 mm.
Titel: |
Composition of Essential Oil from Tagetes minuta and its Cytotoxic, Antioxidant and Antimicrobial Activities
|
---|---|
Autor/in / Beteiligte Person: | Ali Gamal Al-kaf ; Wessjohann, Ludger A. ; Al-Sokari, Saeed S. ; Setzer, William N. ; Arnold, Norbert ; Nasser A. Awadh Ali ; Hill, Gabrielle M. ; Sharopov, Farukh |
Link: | |
Zeitschrift: | Natural Product Communications, Jg. 9 (2014-02-01), S. 1934578X1400900 |
Veröffentlichung: | SAGE Publications, 2014 |
Medientyp: | unknown |
ISSN: | 1555-9475 (print) ; 1934-578X (print) |
DOI: | 10.1177/1934578x1400900233 |
Schlagwort: |
|
Sonstiges: |
|