Satureja hortensisL. Methanolic Extract and Essential Oil Exhibit Antitumor Activity
In: Journal of Essential Oil Bearing Plants, Jg. 19 (2016-01-02), S. 148-154
Online
unknown
Zugriff:
Many members of the genus Satureja have aromatic and medicinal characteristics. Satureja hortensis L. (Lamiaceae) is an Iranian species of Satureja which is well known in Iranian traditional medicine as a remedy for various ailments. In this study, antitumor activity of the essential oil and methanolic extract of S. hortensis was investigated. For antitumor activity tests, a potato disc tumor inhibition method was exploited. Antimicrobial activity of the essential oil and methanolic extract was also studied by a broth microdilution method and MIC values were determined. The methanolic extract exhibited antitumor activity in a concentration dependent manner but the tumor inhibitory effect was significant (> 20 %) at 1 mg/ml and higher. The IC value of the extract was 1.8 mg/ml. The essential oil exhibited tumor growth inhibition (100 %) at dilutions of 0.001 and 0.0001 (v/v). These results demonstrated that S. hortensis has beneficial effects by inhibition of tumor growth on potato discs, which is ...
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Satureja hortensisL. Methanolic Extract and Essential Oil Exhibit Antitumor Activity
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Autor/in / Beteiligte Person: | Khazaie, Maryam ; Ramezani, Mohammad ; Behravan, Javad ; Ehtesham-Gharaee, Melika |
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Zeitschrift: | Journal of Essential Oil Bearing Plants, Jg. 19 (2016-01-02), S. 148-154 |
Veröffentlichung: | Informa UK Limited, 2016 |
Medientyp: | unknown |
ISSN: | 0976-5026 (print) ; 0972-060X (print) |
DOI: | 10.1080/0972060x.2015.1060872 |
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