Antibacterial Activity of Endostemon tereticaulis (Poir.) M. Ashby Essential Oil and Ethanolic Extract Against Resistant Pathogenic Bacteria

Amadou Tidjani Ilagouma ; Bala Namata Abba ; et al.

In: Natural Product Communications, Jg. 15 (2020-09-01), S. 1934578X2095325

Online unknown

Zugriff:

Endostemon tereticaulis (poir.) M.Ashby is a species of the Lamiaceae family present in Niger. This plant is used in traditional medicine due to its various biological potentialities. The present study investigated the chemical composition of the essential oil and the antibacterial activity of the essential oil and ethanolic extract of Endostemon tereticaulis against resistant pathogenic bacteria. Gas chromatography-mass spectrometry analysis of the essential oil led to the identification of 43 compounds representing 99.55% of the total essential oil. The major components were caryophyllene oxide (15.17%) followed by α-humulene (13.96%), α-copaene (11.75%), ( E)-β-caryophyllene (8.44%), and δ-cadinene (6.78%). The antibacterial activity was tested against multiresistant Acinetobacter baumannii P1483, Salmonella spp. H1548, extended-spectrum β-lactamase- Escherichia coli Bu8566, Enterobacter cloacae Bu147, Proteus mirabilis Bu190 , Pseudomonas aeruginosa (ATCC 27853), Klebsiella pneumoniae (ATCC 700603), Escherichia coli (ATCC 25922), Enterococcus faecium H3434, methicillin-resistant Staphylococcus aureus P1123, and Staphylococcus aureus (ATCC 25923). The antibacterial assays revealed that the essential oil was more active than the ethanolic extract against the studied bacteria with minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values ranging from 0.06 to 2 mg/mL. Also, the ethanolic extract was effective against the bacteria tested with MIC and MBC values ranging from 0.12 to 3 mg/mL. This study showed that Endostemon tereticaulis essential oil is rich in bioactive compounds. Ethanolic extract and essential oil exhibited potential antibacterial activity. These results provide a scientific basis for the use of this plant in traditional medicine. The current study described for the first time the antibacterial activity of Endostemon tereticaulis.

Titel:	Antibacterial Activity of Endostemon tereticaulis (Poir.) M. Ashby Essential Oil and Ethanolic Extract Against Resistant Pathogenic Bacteria
Autor/in / Beteiligte Person:	Amadou Tidjani Ilagouma ; Bala Namata Abba ; Romane, Abderrahmane
Link:	View record at OpenAIRE (Volltext) https://doi.org/10.1177/1934578x20953252
Zeitschrift:	Natural Product Communications, Jg. 15 (2020-09-01), S. 1934578X2095325
Veröffentlichung:	SAGE Publications, 2020
Medientyp:	unknown
ISSN:	1555-9475 (print) ; 1934-578X (print)
DOI:	10.1177/1934578x20953252
Schlagwort:	Pharmacology food.ingredient Traditional medicine biology 010405 organic chemistry Pathogenic bacteria Plant Science General Medicine biology.organism_classification medicine.disease_cause 01 natural sciences 0104 chemical sciences law.invention Multiple drug resistance 010404 medicinal & biomolecular chemistry Endostemon food Complementary and alternative medicine law Drug Discovery medicine Lamiaceae Antibacterial activity Essential oil
Sonstiges:	Nachgewiesen in: OpenAIRE Rights: OPEN

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