Epidemiology of essential tremor
In: Oxford Textbook of Neurologic and Neuropsychiatric Epidemiology; (2020-10-01)
Online
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Zugriff:
This chapter on essential tremor (ET) summarizes the current state of knowledge about the epidemiology of this chronic, progressive neurological disease. Case definition is particularly challenging in ET for a variety of reasons and there are several additional methodological considerations that complicate studies of the epidemiology of ET. The adjusted annual incidence rate of ET among persons >65 years old is 616/100,000. The crude prevalence of ET (all ages) is 0.4%, and among persons 60–65 and older, is 6.3%. Risk factors for ET include age and family history of ET. Several other potential risk factors have been studied, including environmental toxins (lead) and dietary exposures (harmane, ethanol). Cigarette smoking may be protective. The search for ET genes is ongoing. Collectively, the data suggest that the LINGO1 SNP rs9652490 confers a modest risk for ET. The identification of such environmental risk factors and susceptibility genes for ET is vitally important.
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Epidemiology of essential tremor
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Autor/in / Beteiligte Person: | Louis, Elan D. |
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Quelle: | Oxford Textbook of Neurologic and Neuropsychiatric Epidemiology; (2020-10-01) |
Veröffentlichung: | Oxford University Press, 2020 |
Medientyp: | unknown |
DOI: | 10.1093/med/9780198749493.003.0016 |
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