Chemical Compositions of Essential Oil of Gailonia aucheri from Iran and it's Antimicrobial and Antioxidant Activities and Total Phenol Contact

The composition of the essential oil obtained from the dried flowering aerial parts of Gailonia aucheri (Rubiaceae) was analyzed by GC and GC–MS. Thirty-three components have been identified in the essential oil of G. aucheri. The major components of the essential oil were myristicin (32.8), oleic acid (9.2) and trans-ocimene (6.3%). The antimicrobial activity of G. aucheri oil was studied using the determination of minimal inhibitory concentration (MIC) values. The plant showed a moderate antimicrobial activity against the tested microorganisms. Best activities can be seen against Staphylococcus epidermis (Gram-positive bacteria), Escherichia coli (Gram-negative bacteria), and Aspergillus niger (fungi) with MIC values of 8, 16, and 8 mg/ml, respectively. In the DPPH radical scavenging assay, the plant oil showed the strong activities with IC50 values of 7.1 mg/ml. Antioxidant activity correlated well with the total phenolic content of the plant oil.