In vitro antiproliferative activity of Melissa officinalis L (Lamiaceae) leaves essential oil
In: Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, Jg. 18 (2019), S. 480-491
Online
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Zugriff:
In the present study, we investigated the antiproliferative activity of essential oil from leaves of Melissa officinalis L. grown in Southern Bosnia and Herzegovina. In vitro evaluation of antiproliferative activity of the M. officinalis essential oil was carried out on three human tumor cell lines: MCF-7, NCI-H460 and MOLT-4 by MTT assay. M. officinalis essential oil was characterized by high percentage of monoterpenes (77,5%), followed by the sesquiterpene fraction (14,5%) and aliphatic compounds (2,2%). The main constituents of the essential oil of M. officinalis are citral (47,2%), caryophyllene oxide (10,2%), citronellal (5,4%), geraniol (6,6%), geranyl acetate (4,1%) and β- caryophyllene (3,8%). The essential oil showed significant antiproliferative activity against three cancer cell lines, MOLT-4, MCF-7, and NCI-H460 cells, with GI50 values of
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In vitro antiproliferative activity of Melissa officinalis L (Lamiaceae) leaves essential oil
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| Autor/in / Beteiligte Person: | Omeragic, Elma ; Niksic, Haris ; Durić, Kemal ; Koric, Emina ; Kusturica, Jasna ; Sijamic, Irma ; Muratović, Samija |
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| Zeitschrift: | Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, Jg. 18 (2019), S. 480-491 |
| Veröffentlichung: | MS-Editions, 2019 |
| Medientyp: | unknown |
| ISSN: | 0717-7917 (print) |
| DOI: | 10.35588/blacpma.19.18.5.31 |
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