FoxO factors are essential for maintaining organ homeostasis by acting as stress sensors in airway epithelial cells.
In: Genomics & Genetics Weekly, 2024-02-23, S. 480-480
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Zugriff:
According to a preprint abstract, FoxO factors play a crucial role in maintaining the balance and function of airway epithelial cells (AECs) in the face of various stressors. These transcription factors act as sensors, translating both external and internal information into appropriate physiological responses. The study found that FoxO factors in Drosophila, mouse, and human AECs respond to stressors such as hypoxia, temperature, and oxidative stress by moving into the nucleus. The absence or reduced expression of FoxO factors in AECs was associated with increased stress sensitivity and may contribute to the development of diseases like asthma. However, it is important to note that this preprint has not yet undergone peer review. [Extracted from the article]
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FoxO factors are essential for maintaining organ homeostasis by acting as stress sensors in airway epithelial cells.
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Zeitschrift: | Genomics & Genetics Weekly, 2024-02-23, S. 480-480 |
Veröffentlichung: | 2024 |
Medientyp: | serialPeriodical |
ISSN: | 1531-6467 (print) |
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