Impact of Essential Hypertension and Diabetes Mellitus on Left Ventricular Systolic and Diastolic Performance☆.
In: European Journal of Echocardiography, Jg. 4 (2003-12-06), Heft 4, S. 306-312
academicJournal
Zugriff:
Aims: To investigate left ventricular systolic and diastolic function in patients with essential hypertension and diabetes mellitus associated with hypertension by the myocardial performance index (MPI).Methods and Results: The study included 45 patients with essential hypertension, 45 patients with diabetes mellitus and hypertension and 45 normal subjects, who underwent a complete two-dimensional and Doppler echocardiography including assessment of the isovolumetric Doppler time intervals for the estimation of the Doppler-derived MPI.The MPI was significantly higher in patients with essential hypertension and diabetes with hypertension, compared to controls (Essential hypertension=0.51±0.12; Diabetes=0.51±0.12 vs. controls 0.40±0.05, P=0.001). The isovolumetric contraction time was significantly prolonged in essential hypertension (56±26 msec vs. 40±17 msec, P<0.01 respectively) and among diabetes patients isovolumetric relaxation time was prolonged compared to normal subjects (100±20 ms vs. 87±16 ms, P<0.01, respectively). The index was not related to left ventricular mass, age or ejection fraction, but significantly correlated to E-wave deceleration time (ρ=0.48, P<0.001)Conclusions: The MPI is increased, in both essential hypertensive patients and diabetes patients with associated hypertension, despite normal ejection fraction. [ABSTRACT FROM AUTHOR]
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Titel: |
Impact of Essential Hypertension and Diabetes Mellitus on Left Ventricular Systolic and Diastolic Performance☆.
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Autor/in / Beteiligte Person: | Andersen, N. H. ; Poulsen, S. H. ; Helleberg, K. ; Ivarsen, P. ; Knudsen, S. T. ; Mogensen, C. E. |
Zeitschrift: | European Journal of Echocardiography, Jg. 4 (2003-12-06), Heft 4, S. 306-312 |
Veröffentlichung: | 2003 |
Medientyp: | academicJournal |
ISSN: | 1525-2167 (print) |
DOI: | 10.1016/S1525-2167(03)00034-9 |
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