Characterization and Evaluation of the In Vitro Antioxidant, α-Glucosidase Inhibitory Activities of Camellia longii Orel and Luu. (Theaceae) Flower Essential Oil and Extracts From Vietnam.
In: Natural Product Communications, Jg. 18 (2023-11-01), Heft 11, S. 1-8
academicJournal
Zugriff:
Objective/Background: Camellia longii Orel and Luu was discovered for the first time in Cat Tien National Park of Lam Dong Province, Southern Vietnam, was determined as a new species. To the best of our knowledge, this is the first report on the phytochemical and bioactivity of this species. Methods: The chemical profile of essential oil (EO) prepared from C. longii flowers was determined by GC/MS analysis and comparison of the recorded retention indices and the corresponding literature values. The total phenolic and flavonoid contents in different flower extracts were estimated by Folin-Ciocalteu and aluminum chloride methods with a spectrophotometer, respectively. The antioxidant activities of the extracts were determined by various bioassays, including DPPH free radical scavenging, ferric reducing power, and cupric reducing antioxidant capacity. The α-glucosidase inhibitory activity of the extracts was evaluated using p-nitrophenyl α-D-glucopyranoside solution as a substrate and acarbose as the positive control. Results: Fifty-seven compounds were identified from the EO of C. longii flowers. Among these, the main components were α-eudesmol (16.1%), followed by (E)-nerolidol (13.0%), β-eudesmol (8.9%), τ-cadinol (6.5%), and γ-eudesmol (5.8%). The total phenolic and flavonoid contents were found high in ethyl acetate, n-butanol, and ethanol extracts (206.8-378.6 mg gallic acid equivalents/g crude extract and 298.5-390.3 mg rutin equivalents/g crude extract, respectively). These extracts were shown to possess potent antioxidant activities in the examined bioassays. As for the α-glucosidase inhibitory assay, the ethyl acetate, butanol, and ethanol extracts were shown to be more potent than acarbose with IC50 values of 2.16 ±0.04, 1.95±0.05, and 1.53 ±0.04 μg/mL, respectively. Conclusion: The findings first provide the phytochemical profiles of Camellia longii Orel and Luu and its bioactivities, indicating moderate potentials in antioxidant activity and strong α-glucosidase inhibition. [ABSTRACT FROM AUTHOR]
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Titel: |
Characterization and Evaluation of the In Vitro Antioxidant, α-Glucosidase Inhibitory Activities of Camellia longii Orel and Luu. (Theaceae) Flower Essential Oil and Extracts From Vietnam.
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Autor/in / Beteiligte Person: | Tran-Trung, Hieu ; Thi Chung Nguyen ; Vo Cong Dung ; Hieu Nguyen Ngoc ; Dang Khoa Nguyen ; Danh Cong Vu ; Son Dang Van ; Quynh Anh Thai Nguyen ; Trang Ha Dieu Nguyen ; Vo Mong Tham ; Xuan Duc Dau |
Zeitschrift: | Natural Product Communications, Jg. 18 (2023-11-01), Heft 11, S. 1-8 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1934-578X (print) |
DOI: | 10.1177/1934578X231208348 |
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