Virucidal Activity of Essential Oils From Citrus x aurantium L. Against Influenza A Virus H1N1: Limonene as a Potential Household Disinfectant Against Virus.
In: Natural Product Communications, Jg. 17 (2022), Heft 1, S. 1-7
academicJournal
Zugriff:
This work explored the compositions of a crude extract of peels of Citrus x aurantium using a gas chromatography-mass spectrometry (GC-MS) technique. The crude extract of peels of C. × aurantium was analyzed by GC-MS revealing the presence of limonene as the major compound, accounting for 93.7% of the total. Virucidal activity of the oil of C. x aurantium peels against influenza A virus H1N1 was evaluated by the ASTM E1053-20 method. Moreover, the virucidal activity was also investigated of D-limonene, the major terpene in essential oils of C. x aurantium, and its enantiomer L-limonene. The essential oil of the C. x aurantium peels produced a log reduction of 1.9 to 2.0, accounting for 99% reduction of the virus, while D- and L-limonene exhibited virucidal activity with a log reduction of 3.70 to 4.32 at concentrations of 125 and 250.0 µg/mL, thus reducing the virus by 99.99%. Previous work found that D-limonene exhibited antiviral activity against herpes simplex virus, but L-limonene, an enantiomer of D-limonene, has never been reported for antiviral activity. This work demonstrates the antiviral activity of L-limonene for the first time. Moreover, this work suggests that concentrations of 0.0125% to 0.025% of either D- or L-limonene can possibly be used as a disinfectant against viruses, probably in the form of essential oil sprays, which may be useful disinfectants against the airborne transmission of viruses, such as influenza and COVID-19. [ABSTRACT FROM AUTHOR]
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Titel: |
Virucidal Activity of Essential Oils From Citrus x aurantium L. Against Influenza A Virus H1N1: Limonene as a Potential Household Disinfectant Against Virus.
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Autor/in / Beteiligte Person: | Fadilah, Nurul Q. ; Jittmittraphap, Akanitt ; Leaungwutiwong, Pornsawan ; Pripdeevech, Patcharee ; Dhanushka, Darshana ; Mahidol, Chulabhorn ; Ruchirawat, Somsak ; Kittakoop, Prasat |
Zeitschrift: | Natural Product Communications, Jg. 17 (2022), Heft 1, S. 1-7 |
Veröffentlichung: | 2022 |
Medientyp: | academicJournal |
ISSN: | 1934-578X (print) |
DOI: | 10.1177/1934578X211072713 |
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