[Calcium antagonist vs diuretics. Doppler velocimetric monitoring of the carotid flow in patients with essential hypertension].

Bellisi, M ; Castellini, E ; et al.

In: Minerva cardioangiologica, Jg. 46 (1998), Heft 1-2, S. 9-14

academicJournal

Background: In the period from 1995 to 1996, 19 patients with a range of 180-200 mmHg and 95-110 mmHg respectively for systolic and diastolic pressure, have been examined by Doppler monitoring.

Methods: Nine patients were treated with lacidipine (4 mg/die) and 10 were treated with idroclorotiazide + amiloride (50 mg every other day). The IPP and the IDC were end points to value the arterial compliance and the remodynamic flow in common carotid.

Results: The humeral blood pressure was valued every morning and Doppler monitoring of common carotid 30 and 60 day after treatment. The carotid blood flow and cerebral perfusion had a significant amelioration with calcium antagonists and an increase of IDC with a decrease of IPP were found.

Conclusions: This study demonstrates the role of calcium antagonists not only as antihypertensive drug, but also to prevent, to check and to improve progression of ateromatic injury. The conclusions is drawn that Doppler monitoring is a satisfactory scientific method to obtain information on features of arterial wall without excessive cost.

Titel:	[Calcium antagonist vs diuretics. Doppler velocimetric monitoring of the carotid flow in patients with essential hypertension].
Autor/in / Beteiligte Person:	Bellisi, M ; Castellini, E ; Trama, PA ; Damiano, A ; Rizza, S ; Stella, C ; Cortese, E
Zeitschrift:	Minerva cardioangiologica, Jg. 46 (1998), Heft 1-2, S. 9-14
Veröffentlichung:	Torino : Edizioni Minerva Medica, 1998
Medientyp:	academicJournal
ISSN:	0026-4725 (print)
Schlagwort:	Adult Blood Pressure Monitoring, Ambulatory Carotid Arteries physiopathology Diuretics Female Humans Hypertension drug therapy Male Middle Aged Ultrasonography, Doppler Calcium Channel Blockers therapeutic use Carotid Arteries drug effects Dihydropyridines therapeutic use Hydrochlorothiazide therapeutic use Hypertension diagnosis Laser-Doppler Flowmetry Sodium Chloride Symporter Inhibitors therapeutic use
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: Italian Transliterated Title: Calcioantagonisti versus diuretici. Monitoraggio velocimetrico Doppler del flusso carotideo nei pazienti con ipertensione essenziale. Publication Type: Clinical Trial; Clinical Trial, Phase II; Comparative Study; English Abstract; Journal Article; Randomized Controlled Trial Language: Italian [Minerva Cardioangiol] 1998 Jan-Feb; Vol. 46 (1-2), pp. 9-14. MeSH Terms: Laser-Doppler Flowmetry* ; Calcium Channel Blockers / therapeutic use ; Carotid Arteries / drug effects ; Dihydropyridines / therapeutic use ; Hydrochlorothiazide / therapeutic use ; Hypertension / diagnosis ; Sodium Chloride Symporter Inhibitors / therapeutic use ; Adult ; Blood Pressure Monitoring, Ambulatory ; Carotid Arteries / physiopathology ; Diuretics ; Female ; Humans ; Hypertension / drug therapy ; Male ; Middle Aged ; Ultrasonography, Doppler Substance Nomenclature: 0 (Calcium Channel Blockers) ; 0 (Dihydropyridines) ; 0 (Diuretics) ; 0 (Sodium Chloride Symporter Inhibitors) ; 0J48LPH2TH (Hydrochlorothiazide) ; 260080034N (lacidipine) Entry Date(s): Date Created: 19981022 Date Completed: 19981105 Latest Revision: 20141120 Update Code: 20231215

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