Chemical composition and anti-proliferative activity of essential oils from some medicinal plants from Cachicadán, Región La Libertad, Perú.
In: Natural product research, Jg. 38 (2024-06-01), Heft 12, S. 2145-2150
academicJournal
Zugriff:
This study evaluated the chemical composition and anti-proliferative activity of essential oils (EOs) obtained by hydrodistillation from seven medicinal plants from Cachicadán, La Libertad Región, Perú. Limonene (0.64 to 44.43%) and linalool (0.36 to 2.12%) were identified in all EOs by gas chromatography coupled to mass spectrometry analysis. The major components (relative intensity ≥ 10%) were cis -dihydro carvone, carvone, and cis -piperitone epoxide for Minthostachys mollis leaves; β-pinene, limonene, and ledol for Lepechinia heteromorpha leaves; limonene, neral, and geranial for Aloysia citriodora , both leaves and flowers; α-pinene, and limonene for Myrcianthes myrsinoides leaves; and α-pinene, β-myrcene, and ( E )-β-Ocimene for Dalea carthagenensis leaves. Constituted by ( Z )-β-ocimene, dihydrotagetone, ( Z )-tagetone, and car-3-en-2-one, EO of Tagetes minuta leaves induced an irreversible cytostatic effect against MCF-7 human breast tumor cells. Further in vivo studies must be carried out to establish the safe and efficient dose of T. minuta EO as adjuvant treatment in oncological therapies.
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Chemical composition and anti-proliferative activity of essential oils from some medicinal plants from Cachicadán, Región La Libertad, Perú.
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Autor/in / Beteiligte Person: | Vaca Meza, ET ; Vasquez-Kool, J ; Costilla Sánchez, NI ; Vieira, A ; Rodrigues, RAF ; Sartoratto, A ; Flores Granados, ADP ; Marin Tello, CL ; Ruiz, ALTG |
Zeitschrift: | Natural product research, Jg. 38 (2024-06-01), Heft 12, S. 2145-2150 |
Veröffentlichung: | Milton Park, UK : Taylor & Francis Health Sciences, c2003-, 2024 |
Medientyp: | academicJournal |
ISSN: | 1478-6427 (electronic) |
DOI: | 10.1080/14786419.2023.2238114 |
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