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Combating antimicrobial resistance (AMR) is among the 10 global health issues identified by the World Health Organization (WHO) in 2021. While AMR is a naturally occurring process, the inappropriate use of antibiotics in different settings and legislative gaps has led to its rapid progression. As a result, AMR has grown into a serious global menace that impacts not only humans but also animals and, ultimately, the entire environment. Thus, effective prophylactic measures, as well as more potent and non-toxic antimicrobial agents, are pressingly needed. The antimicrobial activity of essential oils (EOs) is supported by consistent research in the field. Although EOs have been used for centuries, they are newcomers when it comes to managing infections in clinical settings; it is mainly because methodological settings are largely non-overlapping and there are insufficient data regarding EOs' in vivo activity and toxicity. This review considers the concept of AMR and its main determinants, the modality by which the issue has been globally addressed and the potential of EOs as alternative or auxiliary therapy. The focus is shifted towards the pathogenesis, mechanism of resistance and activity of several EOs against the six high priority pathogens listed by WHO in 2017, for which new therapeutic solutions are pressingly required.

Competing Interests: The authors declare no conflict of interest.

Titel:	Current State of Knowledge Regarding WHO High Priority Pathogens-Resistance Mechanisms and Proposed Solutions through Candidates Such as Essential Oils: A Systematic Review.
Autor/in / Beteiligte Person:	Romanescu, M ; Oprean, C ; Lombrea, A ; Badescu, B ; Teodor, A ; Constantin, GD ; Andor, M ; Folescu, R ; Muntean, D ; Danciu, C ; Dalleur, O ; Batrina, SL ; Cretu, O ; Buda, VO
Zeitschrift:	International journal of molecular sciences, Jg. 24 (2023-06-04), Heft 11
Veröffentlichung:	Basel, Switzerland : MDPI, [2000-, 2023
Medientyp:	academicJournal
ISSN:	1422-0067 (electronic)
DOI:	10.3390/ijms24119727
Schlagwort:	Animals Humans Drug Resistance, Bacterial Anti-Bacterial Agents pharmacology Anti-Bacterial Agents therapeutic use World Health Organization Oils, Volatile pharmacology Oils, Volatile therapeutic use Anti-Infective Agents pharmacology
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Systematic Review; Journal Article; Review Language: English [Int J Mol Sci] 2023 Jun 04; Vol. 24 (11). <i>Date of Electronic Publication: </i>2023 Jun 04. MeSH Terms: Oils, Volatile* / pharmacology ; Oils, Volatile* / therapeutic use ; Anti-Infective Agents* / pharmacology ; Animals ; Humans ; Drug Resistance, Bacterial ; Anti-Bacterial Agents / pharmacology ; Anti-Bacterial Agents / therapeutic use ; World Health Organization References: Med Microbiol Immunol. 2020 Apr;209(2):95-108. (PMID: 31802195) ; EFSA J. 2021 Jun 17;19(6):e06651. (PMID: 34178158) ; Clin Microbiol Rev. 2011 Jan;24(1):71-109. (PMID: 21233508) ; Microb Pathog. 2018 May;118:74-80. (PMID: 29522803) ; Nat Rev Microbiol. 2022 May;20(5):257-269. (PMID: 34737424) ; Microbiol Res. 2021 Jan;242:126608. (PMID: 33068829) ; Front Microbiol. 2016 Oct 04;7:1580. (PMID: 27757108) ; Fitoterapia. 2020 Jan;140:104433. (PMID: 31760066) ; Microb Genom. 2020 Mar;6(3):. (PMID: 32118532) ; Lancet. 2011 Aug 6;378(9790):507-14. (PMID: 21777974) ; Chem Biodivers. 2016 May;13(5):591-5. (PMID: 27038067) ; Clin Vaccine Immunol. 2016 Sep 06;23(9):737-45. (PMID: 27413069) ; Infect Drug Resist. 2018 Nov 15;11:2269-2275. (PMID: 30532561) ; Curr Opin Microbiol. 2020 Feb;53:51-60. (PMID: 32172183) ; BMC Complement Altern Med. 2019 Jan 18;19(1):24. (PMID: 30658640) ; Microb Genom. 2018 Jul;4(7):. (PMID: 29975627) ; Antibiotics (Basel). 2020 Feb 29;9(3):. (PMID: 32121319) ; Antibiotics (Basel). 2020 Nov 09;9(11):. (PMID: 33182474) ; J Mol Recognit. 2017 Jan;30(1):. (PMID: 27594436) ; Transl Res. 2020 Sep;223:76-88. (PMID: 32438073) ; Lett Appl Microbiol. 2019 Feb;68(2):156-164. (PMID: 30471142) ; Int J Med Microbiol. 2020 Jul;310(5):151435. (PMID: 32654773) ; Arch Microbiol. 2021 Sep;203(7):4303-4311. (PMID: 34110480) ; Appl Environ Microbiol. 2016 Sep 30;82(20):6158-6166. (PMID: 27520816) ; Antibiotics (Basel). 2020 Jun 18;9(6):. (PMID: 32570731) ; Vet World. 2019;12(4):504-521. (PMID: 31190705) ; Vet World. 2020 Oct;13(10):2070-2084. (PMID: 33281339) ; Antibiotics (Basel). 2021 Apr 10;10(4):. (PMID: 33920237) ; Molecules. 2019 Aug 27;24(17):. (PMID: 31461850) ; Lancet Infect Dis. 2018 Jul;18(7):717-718. (PMID: 29976521) ; Infect Dis Obstet Gynecol. 2016;2016:5758387. (PMID: 27366021) ; Sci Rep. 2019 Jul 5;9(1):9788. (PMID: 31278344) ; S Afr Med J. 2015 Apr 06;105(5):325. (PMID: 26242647) ; Nat Microbiol. 2021 Jan;6(1):103-111. (PMID: 33106672) ; Crit Rev Food Sci Nutr. 2022;62(19):5267-5283. (PMID: 33554635) ; Nat Rev Mol Cell Biol. 2019 Jun;20(6):353-367. (PMID: 30814649) ; Fitoterapia. 2019 Jul;136:104179. (PMID: 31121252) ; Am J Public Health. 2015 Dec;105(12):2409-10. (PMID: 26469675) ; Biomed Microdevices. 2018 Apr 11;20(2):35. (PMID: 29644437) ; Chem Biodivers. 2019 Nov;16(11):e1900359. (PMID: 31544347) ; Microb Pathog. 2018 Sep;122:117-121. (PMID: 29908309) ; An Acad Bras Cienc. 2020 Dec 14;92(4):e20200456. (PMID: 33331445) ; Curr Opin Infect Dis. 2016 Feb;29(1):45-51. (PMID: 26658656) ; Plants (Basel). 2017 Apr 10;6(2):. (PMID: 28394295) ; Gut Microbes. 2013 Nov-Dec;4(6):541-8. (PMID: 23929066) ; Asian Pac J Trop Med. 2017 Aug;10(8):819-826. (PMID: 28942832) ; Molecules. 2021 Dec 26;27(1):. (PMID: 35011355) ; Clin Infect Dis. 2020 Mar 3;70(6):1240-1246. (PMID: 31504338) ; Antibiotics (Basel). 2021 Jan 18;10(1):. (PMID: 33477717) ; PLoS Med. 2017 Jul 7;14(7):e1002344. (PMID: 28686231) ; J Appl Biomed. 2022 Feb 16;:. (PMID: 35225438) ; Clin Infect Dis. 2006 Jan 1;42 Suppl 1:S40-50. (PMID: 16323119) ; Curr Top Microbiol Immunol. 2016;398:237-272. (PMID: 27738915) ; J Glob Antimicrob Resist. 2016 Mar;4:35-41. (PMID: 27436390) ; J Enzyme Inhib Med Chem. 2022 Dec;37(1):1610-1619. (PMID: 35642325) ; Biomed Res Int. 2017;2017:9082716. (PMID: 29159181) ; Future Microbiol. 2019 Sep;14:1179-1189. (PMID: 31625440) ; Vet Res Forum. 2020 Fall;11(4):333-338. (PMID: 33643585) ; Genome Biol. 2017 Jul 20;18(1):130. (PMID: 28724393) ; Biomed Res Int. 2017;2017:2672689. (PMID: 29230405) ; Plants (Basel). 2022 Jul 06;11(14):. (PMID: 35890423) ; Immunol Lett. 2017 Oct;190:42-50. (PMID: 28720334) ; Clin Microbiol Rev. 2019 Jul 3;32(4):. (PMID: 31270126) ; Evid Based Complement Alternat Med. 2016;2016:3012462. (PMID: 28090211) ; Front Cell Infect Microbiol. 2020 Mar 17;10:107. (PMID: 32257966) ; Biomed Pharmacother. 2019 Jan;109:1650-1658. (PMID: 30551419) ; ACS Omega. 2021 Sep 22;6(39):25652-25663. (PMID: 34632221) ; Phytomedicine. 2019 Apr;57:339-351. (PMID: 30826631) ; Int J Med Microbiol. 2021 Feb;311(2):151477. (PMID: 33524636) ; Helicobacter. 2018 Aug;23(4):e12495. (PMID: 29873436) ; Drug Res (Stuttg). 2016 Dec;66(12):657-659. (PMID: 27626607) ; J Glob Antimicrob Resist. 2020 Mar;20:238-247. (PMID: 31442624) ; Infect Drug Resist. 2018 Feb 26;11:267-274. (PMID: 29520157) ; J Microbiol Immunol Infect. 2022 Dec;55(6 Pt 2):1273-1282. (PMID: 34340908) ; Front Microbiol. 2017 Mar 14;8:299. (PMID: 28352250) ; Antibiotics (Basel). 2022 Jan 14;11(1):. (PMID: 35052985) ; Yale J Biol Med. 2017 Jun 23;90(2):269-281. (PMID: 28656013) ; Nat Rev Dis Primers. 2018 May 31;4:18033. (PMID: 29849094) ; Pathogens. 2021 Oct 12;10(10):. (PMID: 34684258) ; Org Biomol Chem. 2017 Aug 9;15(31):6548-6556. (PMID: 28745773) ; World J Gastroenterol. 2018 Apr 14;24(14):1531-1539. (PMID: 29662291) ; Helicobacter. 2018 Sep;23 Suppl 1:e12514. (PMID: 30203587) ; Curr Opin Microbiol. 2012 Oct;15(5):588-95. (PMID: 23044073) ; mBio. 2022 Apr 26;13(2):e0027622. (PMID: 35258329) ; Molecules. 2019 Dec 26;25(1):. (PMID: 31888005) ; J Nat Prod. 2020 Jul 24;83(7):2207-2211. (PMID: 32558565) ; Int J Anal Chem. 2021 Aug 30;2021:9937522. (PMID: 34497647) ; Nat Rev Microbiol. 2015 Jan;13(1):42-51. (PMID: 25435309) ; Microb Genom. 2018 Jan;4(8):. (PMID: 30024366) ; Antibiotics (Basel). 2018 Jun 15;7(2):. (PMID: 29914071) ; Materials (Basel). 2018 Apr 24;11(5):. (PMID: 29695049) ; Transbound Emerg Dis. 2018 May;65 Suppl 1:30-48. (PMID: 29663680) ; Biomed Res Int. 2021 Oct 11;2021:5247816. (PMID: 34671674) ; Antibiotics (Basel). 2021 Apr 20;10(4):. (PMID: 33923861) ; Microb Pathog. 2018 Sep;122:162-173. (PMID: 29920307) ; Molecules. 2018 Jul 10;23(7):. (PMID: 29996498) ; Infect Drug Resist. 2018 Oct 10;11:1645-1658. (PMID: 30349322) ; Pathogens. 2019 Jan 28;8(1):. (PMID: 30696051) ; Molecules. 2019 Jul 05;24(13):. (PMID: 31284397) ; Lett Appl Microbiol. 2018 Nov;67(5):449-457. (PMID: 30187508) ; Biomed Res Int. 2013;2013:340605. (PMID: 23865047) ; Pathog Glob Health. 2020 Feb;114(1):16-29. (PMID: 32013798) ; Infect Drug Resist. 2019 Sep 02;12:2713-2725. (PMID: 31564921) ; Public Health Rep. 2012 Jan-Feb;127(1):4-22. (PMID: 22298919) ; Biofouling. 2016;32(2):215-25. (PMID: 26838161) ; Plants (Basel). 2022 Jul 27;11(15):. (PMID: 35893649) ; J Pharm Biomed Anal. 2018 Apr 15;152:271-278. (PMID: 29448222) ; EBioMedicine. 2017 Feb;15:100-111. (PMID: 27965105) ; Curr Opin Microbiol. 2019 Oct;51:72-80. (PMID: 31733401) ; Iran J Microbiol. 2022 Feb;14(1):56-66. (PMID: 35664709) ; Molecules. 2021 Oct 26;26(21):. (PMID: 34770858) ; Annu Rev Microbiol. 2017 Sep 8;71:665-686. (PMID: 28886683) ; Nat Rev Microbiol. 2018 Apr;16(4):226-240. (PMID: 29430011) ; Molecules. 2018 Oct 17;23(10):. (PMID: 30336602) ; Nat Rev Gastroenterol Hepatol. 2011 Oct 25;8(12):669-85. (PMID: 22025030) ; J Tradit Complement Med. 2018 Jul 10;9(3):206-214. (PMID: 31193983) ; Nat Rev Chem. 2021 Oct;5(10):726-749. (PMID: 37118182) ; J Cell Mol Med. 2019 Dec;23(12):7919-7925. (PMID: 31536675) ; Foods. 2020 May 05;9(5):. (PMID: 32380674) ; Molecules. 2021 May 02;26(9):. (PMID: 34063264) ; Infect Drug Resist. 2019 Nov 14;12:3537-3548. (PMID: 31814742) ; Front Microbiol. 2019 Aug 13;10:1865. (PMID: 31456779) ; Fitoterapia. 2019 Mar;133:130-136. (PMID: 30654130) ; J Infect Public Health. 2017 Jul - Aug;10(4):369-378. (PMID: 27616769) ; Microbiol Spectr. 2018 Jan;6(1):. (PMID: 29327680) ; Microb Drug Resist. 2019 Jul/Aug;25(6):890-908. (PMID: 30811275) ; Front Cell Infect Microbiol. 2015 Jan 28;5:1. (PMID: 25674541) ; Molecules. 2015 Apr 22;20(4):7329-58. (PMID: 25911964) ; J Ethnopharmacol. 2020 May 10;253:112652. (PMID: 32035880) ; Molecules. 2017 Aug 23;22(9):. (PMID: 28832536) ; Aliment Pharmacol Ther. 2017 Nov;46(9):773-779. (PMID: 28892184) ; J Glob Infect Dis. 2019 Jan-Mar;11(1):36-42. (PMID: 30814834) ; Saudi J Biol Sci. 2021 Sep;28(9):5145-5156. (PMID: 34466092) ; Front Microbiol. 2014 Dec 12;5:706. (PMID: 25566220) ; Saudi Pharm J. 2019 Jul;27(5):612-618. (PMID: 31297014) ; Pharmaceuticals (Basel). 2020 Nov 06;13(11):. (PMID: 33171909) ; Biomed Res Int. 2020 Jul 15;2020:4851879. (PMID: 32733942) ; J Glob Antimicrob Resist. 2022 Jun;29:163-167. (PMID: 35288333) ; Curr Microbiol. 2019 Jan;76(1):108-116. (PMID: 30421144) ; Biomed Res Int. 2016;2016:8701067. (PMID: 27088092) ; Antibiotics (Basel). 2021 Jun 08;10(6):. (PMID: 34201299) ; Chem Biodivers. 2017 May;14(5):. (PMID: 28190283) ; BMC Complement Altern Med. 2016 Oct 26;16(1):418. (PMID: 27782845) ; PLoS One. 2020 Apr 1;15(4):e0230423. (PMID: 32236115) ; Int J Mol Sci. 2022 Jul 22;23(15):. (PMID: 35897667) ; Phytochem Anal. 2021 Sep;32(5):820-835. (PMID: 33462938) ; Pharmacogn Mag. 2017 Oct;13(Suppl 3):S446-S451. (PMID: 29142397) ; Evid Based Complement Alternat Med. 2021 Mar 15;2021:6643765. (PMID: 33790979) ; Lancet Planet Health. 2023 Apr;7(4):e291-e303. (PMID: 37019570) ; BMC Complement Altern Med. 2017 Sep 16;17(1):462. (PMID: 28915875) ; Antibiotics (Basel). 2021 Jan 21;10(2):. (PMID: 33494538) ; Molecules. 2021 Jul 31;26(15):. (PMID: 34361815) ; Medicines (Basel). 2016 Sep 22;3(4):. (PMID: 28930135) ; Nat Prod Res. 2020 May;34(9):1311-1314. (PMID: 30618269) ; Microb Pathog. 2017 May;106:50-59. (PMID: 27815129) ; Arch Microbiol. 2021 Sep;203(7):4727-4736. (PMID: 34052872) ; Molecules. 2019 Oct 28;24(21):. (PMID: 31661884) ; BMC Complement Med Ther. 2021 May 17;21(1):143. (PMID: 34001110) ; Drug Discov Ther. 2017 May 30;11(2):78-83. (PMID: 28458299) ; J Food Sci. 2016 Feb;81(2):E419-29. (PMID: 26749466) ; Int J Microbiol. 2020 Oct 30;2020:8868197. (PMID: 33488728) ; Antibiotics (Basel). 2021 Nov 03;10(11):. (PMID: 34827280) ; Infect Dis Clin North Am. 2021 Mar;35(1):107-133. (PMID: 33303331) ; J Biomed Sci. 2018 Sep 11;25(1):68. (PMID: 30205817) ; J Tradit Chin Med. 2017 Feb;37(1):57-63. (PMID: 29956906) ; Clin Microbiol Rev. 2018 Sep 12;31(4):. (PMID: 30209034) ; PLoS Negl Trop Dis. 2019 Mar 18;13(3):e0007187. (PMID: 30883544) ; Lancet Infect Dis. 2019 Dec;19(12):1312-1324. (PMID: 31562022) ; Antibiotics (Basel). 2020 Oct 24;9(11):. (PMID: 33114324) ; BMJ. 2018 Nov 12;363:k3047. (PMID: 30420401) ; Molecules. 2020 Jan 29;25(3):. (PMID: 32013183) ; Methods Mol Biol. 2014;1085:131-48. (PMID: 24085694) ; AIMS Microbiol. 2021 Jun 24;7(2):238-256. (PMID: 34250377) ; Recent Pat Biotechnol. 2018;12(3):158-168. (PMID: 29210667) ; Int J Mol Sci. 2020 Sep 26;21(19):. (PMID: 32993130) ; Microb Genom. 2019 Jul;5(7):. (PMID: 31329096) ; Molecules. 2021 Dec 13;26(24):. (PMID: 34946632) ; Ann Pharmacother. 2020 Dec;54(12):1243-1251. (PMID: 32506921) ; Ci Ji Yi Xue Za Zhi. 2018 Jul-Sep;30(3):135-140. (PMID: 30069120) ; Front Microbiol. 2021 Mar 29;12:610656. (PMID: 33854486) ; J Intercult Ethnopharmacol. 2016 May 04;5(3):250-6. (PMID: 27366351) ; Virulence. 2021 Dec;12(1):547-569. (PMID: 33522395) ; Antimicrob Resist Infect Control. 2020 Aug 10;9(1):130. (PMID: 32778149) ; Molecules. 2019 Jul 19;24(14):. (PMID: 31330955) ; Phytother Res. 2020 Jul;34(7):1638-1649. (PMID: 32045500) ; Gut. 2015 Sep;64(9):1353-67. (PMID: 26187502) ; World J Plast Surg. 2016 Sep;5(3):259-264. (PMID: 27853689) ; Environ Pollut. 2021 Sep 15;285:117402. (PMID: 34051569) ; Molecules. 2019 Jun 09;24(11):. (PMID: 31181843) ; Nutrients. 2020 Apr 04;12(4):. (PMID: 32260414) ; Antibiotics (Basel). 2021 Aug 15;10(8):. (PMID: 34439033) ; Phytother Res. 2019 Apr;33(4):1010-1018. (PMID: 30672036) ; Front Microbiol. 2021 May 06;12:663731. (PMID: 34025618) ; BMC Complement Med Ther. 2020 Mar 17;20(1):89. (PMID: 32183792) ; J Glob Antimicrob Resist. 2019 Mar;16:36-47. (PMID: 30149193) ; Pediatrics. 2021 Jan;147(1):. (PMID: 33372120) ; Braz J Microbiol. 2017 Oct - Dec;48(4):617-628. (PMID: 28754299) ; Medicines (Basel). 2017 Aug 08;4(3):. (PMID: 28930272) ; J Eval Clin Pract. 2012 Apr;18(2):473-84. (PMID: 21210896) ; ScientificWorldJournal. 2022 Feb 28;2022:8418287. (PMID: 35264915) ; Ann Intern Med. 2019 Aug 20;171(4):257-263. (PMID: 31330541) ; Nanomaterials (Basel). 2018 Apr 30;8(5):. (PMID: 29710862) ; Phytochem Anal. 2019 Mar;30(2):121-131. (PMID: 30280447) ; Nat Prod Res. 2018 Jun;32(11):1299-1302. (PMID: 28627304) ; Clin Infect Dis. 2011 Feb 1;52(3):e18-55. (PMID: 21208910) ; Food Chem. 2022 Jul 15;382:132312. (PMID: 35158267) ; Anim Health Res Rev. 2017 Dec;18(2):87-98. (PMID: 29166961) ; Emerg Microbes Infect. 2020 Dec;9(1):1180-1193. (PMID: 32498615) ; Molecules. 2016 Apr 28;21(5):. (PMID: 27136520) Contributed Indexing: Keywords: cephalosporin-resistant; clarithromycin-resistant Helicobacter pylori; fluoroquinolone-resistant Campylobacter spp.; fluoroquinolone-resistant Neisseria gonorrhoeae; fluoroquinolone-resistant Salmonellae; methicillin-resistant; multidrug-resistant strains; nosocomial infections; vancomycin-resistant Enterococcus faecium; vancomycin-resistant Staphylococcus aureus Substance Nomenclature: 0 (Oils, Volatile) ; 0 (Anti-Bacterial Agents) ; 0 (Anti-Infective Agents) Entry Date(s): Date Created: 20230610 Date Completed: 20230612 Latest Revision: 20230612 Update Code: 20240514 PubMed Central ID: PMC10253476

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Current State of Knowledge Regarding WHO High Priority Pathogens-Resistance Mechanisms and Proposed Solutions through Candidates Such as Essential Oils: A Systematic Review.