| Sonstiges: |
- Nachgewiesen in: MEDLINE
- Sprachen: English
- Publication Type: Journal Article
- Language: English
- [Environ Sci Pollut Res Int] 2018 Oct; Vol. 25 (29), pp. 29144-29161. <i>Date of Electronic Publication: </i>2018 Aug 15.
- MeSH Terms: Aflatoxin B1 / *toxicity ; Cinnamomum zeylanicum / *chemistry ; Fumonisins / *toxicity ; Plant Oils / *pharmacology ; Protective Agents / *pharmacology ; Animals ; DNA Fragmentation ; Gas Chromatography-Mass Spectrometry ; Kidney / drug effects ; Liver / drug effects ; Male ; Oils, Volatile / analysis ; Oils, Volatile / chemistry ; Oils, Volatile / pharmacology ; Oxidative Stress / drug effects ; Plant Oils / analysis ; Plant Oils / chemistry ; Rats, Sprague-Dawley ; Testis / drug effects ; Toxicity Tests, Subchronic ; Whey Proteins / chemistry
- References: Abbès S, Ben Salah-Abbès J, Jebali R, Younes RB, Oueslati R (2016) Interaction of aflatoxin B 1 and fumonisin B 1 in mice causes immunotoxicity and oxidative stress: possible protective role using lactic acid bacteria. J Immunotoxicol 13(1):46–54. (PMID: 10.3109/1547691X.2014.997905) ; Abdel-Latif MS, Elmeleigy KM, Aly TA, Khattab MS, Mohamed SM (2017) Pathological and biochemical evaluation of coumarin and chlorophyllin against aflatoxicosis in rat. Exp Toxicol Pathol. https://doi.org/10.1016/j.etp.2017.01.014. ; Abdel-Wahhab MA, Hassan NS, El-Kady AA, Mohamed YA, El-Nekeety AA, Mohamed SR, Sharaf HA, Mannaa FA (2010) Red ginseng extract protects againist aflatoxin B 1 and fumonisins induced hepatic pre-cancerous lesions in rats. Food Chem Toxicol 48:733–742. (PMID: 10.1016/j.fct.2009.12.006) ; Abdel-Wahhab MA, Ibrahim AA, El-Nekeety AA, Hassan NS, Mohamed AA (2012) Panax ginseng C.A. Meyer extract counteracts the oxidative stress in rats fed multi-mycotoxins-contaminated diet. Comunicata Scientiae 3(3):143–153. ; Adams RP (2001) Identification of essential oil components by gas chromatography/ mass spectrometry. Allured, Carol Stream. ; Adedara IA, Owumi SE, Uwaifo AO, Farombi EO (2010) Aflatoxin B 1 and ethanol co-exposure induces hepatic oxidative damage in mice. Toxicol Ind Health 26:717–724. (PMID: 10.1177/0748233710377772) ; Adeleye AO, Ajiboye TO, Iliasu GA, Abdussalam FA, Balogun A, Ojewuyi OB, Yakubu MT (2014) Phenolic extract of Dialium guineense pulp enhances reactive oxygen species detoxification in aflatoxin B 1 hepatocarcinogenesis. J Med Food 17(8):875–885. (PMID: 10.1089/jmf.2013.0157) ; Agarwal S, Mathur M, Srivastava A, Ralhan R (1999) MDM2/p53 co-expression in oral premalignant and malignant lesions: potential prognostic implications. Eur J Cancer Oral Oncol 35:209–216. ; Agnes VF, Akbarsha MA (2003) Spermatotoxic effect of aflatoxin B 1 in the albino mouse. Food Chem Toxicol 41:119–130. (PMID: 10.1016/S0278-6915(02)00171-0) ; Ajiboye TO, Yakubu MT, Oladiji AT (2016) Lophirones B and C prevent aflatoxin B 1 -induced oxidative stress and DNA fragmentation in rat hepatocytes. Pharm Biol 54(10):1962–1970. (PMID: 10.3109/13880209.2015.1137603) ; Antonsson B (2004) Mitochondria and the Bcl-2 family proteins in apoptosis signaling pathways. Mol Cell Biochem 256(1–2):141–155. (PMID: 10.1023/B:MCBI.0000009865.70898.36) ; Baek NL, Kim YS, Kyung JS, Park KH (1996) Isolation of anti-hepatotoxic agents from the roots of Astralagus membranaceous. Korean J Pharmacog 27:111–116. ; Bayrama T, Pekmez M, Arda N, Yalcın AS (2009) Antioxidant activity of whey protein fractions isolated by gel exclusion chromatography and protease treatment. Talanta 75:705–709. (PMID: 10.1016/j.talanta.2007.12.007) ; Bhatnagar-Mathur P, Sunkara S, Bhatnagar-Panwar M, Waliyar F, Sharma KK (2015) Biotechnological advances for combating Aspergillus flavus and aflatoxin contamination in crops. Plant Sci 234:119–132. (PMID: 10.1016/j.plantsci.2015.02.009) ; Bilia AR, Guccione C, Isacchi B, Righeschi C, Firenzuoli F, Bergonzi MC (2014) Essential oils loaded in nanosystems: a developing strategy for a successful therapeutic approach. Evid Based Complement Alternat Med 2014:651593. ; Blevins SM, Leyva MJ, Brown J, Wright J, Scofield RH, Aston CE (2007) Effect of cinnamon on glucose and lipid levels in non insulin-dependent type 2 diabetes. Diabetes Care 30(9):2236–2237. (PMID: 10.2337/dc07-0098) ; Bounous G (2000) Whey protein concentrate (WPC) and glutathione modulation in cancer treatment. Anticancer Res 20:4785–4792. ; Bounous G, Gervais F, Amer V, Batist G, Gold P (1989) The influence of dietary whey protein on tissue glutathione and disease of aging. Clin Invest Med 12:343–349. ; Brr AAH, Mahmoud YAG (2005) Anti-yeast effects of some plant extracts on yeasts contaminating processed poultry products in Egypt. Czech J Food Sci 23:12–19. (PMID: 10.17221/3366-CJFS) ; Cansell M, Nacka F, Combe N (2003) Marine lipid-based liposomes increase in vivo FA bioavailability. Lipids 38:551–559. (PMID: 10.1007/s11745-003-1341-0) ; Cao Z, Shao B, Xu F, Liu Y, Li Y, Zhu Y (2017) Protective effect of selenium on aflatoxin B 1 -induced testicular toxicity in mice. Biol Trace Elem Res 180(2):233–238. (PMID: 10.1007/s12011-017-0997-z) ; CAST (2003) Mycotoxins: risks in plant, animal, and human systems, Council for Agricultural Science and Technology Task Force report No. 139. Ames, Iowa, USA. ; Chang WL, Cheng FC, Wang SP, Chou ST, Shih Y (2016) Cinnamomum cassia essential oil and its major constituent cinnamaldehyde induced cell cycle arrest and apoptosis in human oral squamous cell carcinoma HSC-3 cells. Environ Toxicol 25. https://doi.org/10.1002/tox.22250. ; Chen KJ, Shu G, Peng X, Fang J, Cui HM, Chen J, Wang FY, Chen ZL, Zuo ZC, Deng JL, Geng Y, Lai WM (2013) Protective role of sodium selenite on histopathological lesions, decreased T-cell subsets and increased apoptosis of thymus in broilers intoxicated with aflatoxin B 1 . Food Chem Toxicol 59:446–454. (PMID: 10.1016/j.fct.2013.06.032) ; Cheng SS, Liu JY, Hsui YR, Chang ST (2006) Chemical polymorphism and antifungal activity of essential oils from leaves of different provenances of indigenous cinnamon (Cinnamomum osmophloeum). Bioresour Technol 97:306–312. (PMID: 10.1016/j.biortech.2005.02.030) ; Chew EH, Nagle AA, Zhang Y, Scarmagnani S, Palaniappan P, Bradshaw TD, Holmgren A, Westwell AD (2010) Cinnamaldehydes inhibit thioredoxin eductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention. Free Radic Biol Med 48:98–111. (PMID: 10.1016/j.freeradbiomed.2009.10.028) ; Chung JW, Kim JJ, Kim SJ (2011) Antioxidative effects of cinnamomi cortex: a potential role of iNOS and COX-II. Pharmacogn Mag 7(28):314–319. (PMID: 10.4103/0973-1296.90412) ; Connell BJ, Chang SY, Prakash E, Yousfi R, Mohan V, Posch W, Wilflingseder D, Moog C, Kodama EN, Clayette P, Lortat-Jacob H (2016) A cinnamon-derived procyanidin compound displays anti-HIV-1 activity by blocking heparan sulfate-and co-receptorbinding sites on gp120 and reverses T cell exhaustion via impeding tim-3 and PD-1 upregulation. PLoS One 11(10):e0165386. (PMID: 10.1371/journal.pone.0165386) ; Contassot E, Beer HD, French LE (2012) Interleukin-1, inflammasomes, auto-inflammation and the skin. Swiss Med Wkly 142:w13590. https://doi.org/10.4414/smw.2012.13590. (PMID: 10.4414/smw.2012.13590) ; Croce CM, Reed JC (2016) Finally, an apoptosis-targeting therapeutic for cancer. Cancer Res 76:5914–5920. (PMID: 10.1158/0008-5472.CAN-16-1248) ; Dejean LM, Martinez-Caballero S, Manon S, Kinnally KW (2006) Regulation of the mitochondrial apoptosis-induced channel, MAC, by Bcl-2 family proteins. Biochim Biophys Acta 1762:191–201. (PMID: 10.1016/j.bbadis.2005.07.002) ; Dinarello CA (2009) Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 27:519–550. (PMID: 10.1146/annurev.immunol.021908.132612) ; Dorri M, Hashemitabar S, Hosseinzadeh H (2018) Cinnamon (Cinnamomum zeylanicum) as an antidote or a protective agent against natural or chemical toxicities: a review. Drug Chem Toxicol 10:1–14. ; Drury RAV, Wallington EA (1980) Carltons Histological techniques, 5th edn. Oxford University Press, New York, Pronto, p 206SY. ; El-Bahr SM (2015) Effect of curcumin on hepatic antioxidant enzymes activities and gene expressions in rats intoxicated with aflatoxin B 1 . Phytother Res 29(1):134–140. (PMID: 10.1002/ptr.5239) ; El-Nekeety AA, Salman AS, Hathout AS, Sabry BA, Abdel-Aziem SH, Hassan NS, Abdel-Wahhab MA (2017) Evaluation of the bioactive extract of actinomyces isolated from the Egyptian environment against aflatoxin B 1 -induce cytotoxicity, genotoxicity and oxidative stress in the liver of rats. Food Chem Toxicol 105:241–255. (PMID: 10.1016/j.fct.2017.04.024) ; Elsaad ASA, Mahmoud HM (2009) Phytic acid exposure alters aflatoxin B 1 -induced reproductive and oxidative toxicity in albino rats (Rattus norvegicus). Evid Based Complement Alternat Med 6(3):331–341. (PMID: 10.1093/ecam/nem137) ; Eratte D, Wang B, Dowling K, Barrow CJ, Adhikari BP (2014) Complex coacervation with whey protein isolate and gum arabic for the microencapsulation of omega-3 rich tuna oil. Food Funct 5:2743–2750. (PMID: 10.1039/C4FO00296B) ; Gad AS, Khadrawy YA, El-Nekeety AA, Mohamed SR, Hassan NS, Abdel-Wahhab MA (2011) Antioxidant activity and hepatoprotective effects of whey protein and spirulina in rats. Nutrition 27(5):582–589. (PMID: 10.1016/j.nut.2010.04.002) ; Gahring LC, Carlson NG, Kulmar RA, Rogers SW (1996) Neuronal expression of tumor necrosis factor alpha in the murine brain. Neuroimmunomodulation 3(5):289–303. (PMID: 10.1159/000097283) ; Goula AM, Adamopoulos KG (2012) A new technique for spray-dried encapsulation of lycopene. Dry Technol 30(6):641–652. (PMID: 10.1080/07373937.2012.655871) ; Guengerich FP, Johnson WW, Shimada T, Ueng YF, Yamazaki H, Langouët S (1998) Activation and detoxication of aflatoxin B 1 . Mutat Res 402:121–128. (PMID: 10.1016/S0027-5107(97)00289-3) ; Hamidpour R, Hamidpour M, Hamidpour S, Shahlari M (2015) Cinnamon from the selection of traditional applications to its novel effects on the inhibition of angiogenesis in cancer cells and prevention of Alzheimer’s disease, and a series of functions such as antioxidant, anticholesterol, antidiabetes, antibacterial, antifungal, nematicidal, acaracidal, and repellent activities. J Tradit Complement Med 5(2):66–70. (PMID: 10.1016/j.jtcme.2014.11.008) ; Harrison LR, Colvin BM, Greene JT, Newman LE, Cole JR (1990) Pulmonary oedema and hydrothorax in swine produced by fumonisin B 1 , a toxic metabolite of Fusarium moniliforme. J Vet Diagn Investig 2:217–221. (PMID: 10.1177/104063879000200312) ; Hasegawa T, Zhao LP, Caron KM, Majdic G, Suzuki T, Shizawa S, Sasano H, Parker KL (2000) Developmental roles of the steroidogenic acute regulatory protein (StAR) as revealed by StAR knockout mice. Mol Endocrinol 14(9):1462–1471. (PMID: 10.1210/mend.14.9.0515) ; Hassan AM, Mohamed SR, El-Nekeety AA, Hassan NS, Abdel-Wahhab MA (2010) Aquilegia vulgaris L extract counteracts oxidative stress and cytotoxicity of fumonisin in rats. Toxicon 56:8–18. (PMID: 10.1016/j.toxicon.2010.03.006) ; Hassan AM, Abdel-Aziem SH, Abdel-Wahhab MA (2012) Modulation of DNA damage and alteration of gene expression during aflatoxicosis via dietary supplementation of Spirulina (Arthrospira) and whey protein concentrate. Ecotoxicol Environ Saf 79:294–300. (PMID: 10.1016/j.ecoenv.2012.01.017) ; Hassan AM, Abdel-Aziem SH, El-Nekeety AA, Abdel-Wahhab MA (2015) Panax ginseng extract modulates oxidative stress, DNA fragmentation and up-regulate gene expression in rats sub chronically treated with aflatoxin B 1 and fumonisin B 1 . Cytotechnology 67:861–871. (PMID: 10.1007/s10616-014-9726-z) ; Heim KE, Tagliaferro AR, Bobilya DJ (2002) Flavonoid antioxidants: chemistry, metabolism and structure–activity relationships. J Nutr Biochem 10:572–584. (PMID: 10.1016/S0955-2863(02)00208-5) ; Hell K, Mutegi C (2011) Aflatoxin control and prevention strategies in key crops of Sub-Saharan Africa. Afr J Microbiol Res 5(5):459–466. ; Hemayatkhah Jahromi V, Parivar K, Forozanfar M (2011) The effect of cinnamon extract on spermatogenesis hormonal axis of pituitary gonad in mice. Iran J Appl Anim Sci 1:99–103. ; IARC (1987) International Agency for Research on Cancer (IARC) monographs on the evaluation of carcinogenic risk of chemicals to humans. In: Overall evaluation of carcinogenicity: an updating of IARC monographs, vols. 1e42 (Suppl. 7). IARC, Lyon, p 59. ; IARC (2012) Monographs on the evaluation of carcinogenic risks to humans: chemical agents and related occupations. A review of human carcinogens, vol 100F. International Agency for Research on Cancer, Lyon, pp 224–248. ; Jardim CM, Jham GN, Dhingra OD, Freire MM (2008) Composition and anti-fungal activity of the essential oil of the Brazilian Chenopodium ambrosioides L. J Chem Ecol 34:1213–1218. (PMID: 10.1007/s10886-008-9526-z) ; Karabacak M, Eraslan G, Kanbur M, Sarıca ZS (2015) Effects of Tarantula cubensis D6 on aflatoxin-induced injury in biochemical parameters in rats. Homeopathy 104(3):205–210. (PMID: 10.1016/j.homp.2015.02.005) ; Karuna R, Rao BS (2013) Lack of micronuclei induction by fumonisin B1 mycotoxin in BALB/c mice. Mycotoxin Res 29:9–15. (PMID: 10.1007/s12550-012-0149-4) ; Kaul PN, Bhattacharya AK, Rao BRR, Syamasundar KV, Ramesh S (2003) Volatile constituents of essential oils isolated from different parts of cinnamon (Cinnamomum zeylanicum Blume). J Sci Food Agric 83:53–55. (PMID: 10.1002/jsfa.1277) ; Kent KD, Harper WJ, Bomser JA (2003) Effect of whey protein isolate on intracellular glutathione and oxidant-induced cell death in human prostate epithelial cells. Toxicol in Vitro 17:27–33. (PMID: 10.1016/S0887-2333(02)00119-4) ; Khasnavis S, Pahan K (2012) Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. J NeuroImmune Pharmacol 7(2):424–435. (PMID: 10.1007/s11481-011-9286-3) ; Kourousekos GD, Theodosiadou EK, Lymberopoulos AG, Belibasaki S, Boscos C (2015) Effect of prolonged aflatoxin B 1 administration on blood serum oestradiol-17β and progesterone concentrations of goats during the anoestrus period. Czech J Anim Sci 60(4):164–170. (PMID: 10.17221/8130-CJAS) ; Kreydiyyeh SI, Usta J, Copti R (2000) Effect of cinnamon, clove and some of their constituents on the Na + -K + -ATPase activity and alanine absorption in the rat jejunum. Food Chem Toxicol 38:755–762. (PMID: 10.1016/S0278-6915(00)00073-9) ; Kroemer G, Galluzzi L, Brenner C (2007) Mitochondrial membrane permeabilization in cell death. Physiol Rev 87:99–163. (PMID: 10.1152/physrev.00013.2006) ; Kumar P, Mahato DK, Kamle M, Mohanta TK, Kang SG (2017) Aflatoxins: a global concern for food safety, human health and their management. Front Microbiol 7:2170–2177. (PMID: 10.3389/fmicb.2016.02170) ; Ledoux DR, Brown TP, Weibking TS, Rottinghaus GE (1992) Fumonisin toxicity in broiler chicks. J Vet Diagn Investig 4:330–337. (PMID: 10.1177/104063879200400317) ; Lee HJ, Ryu D (2017) Worldwide occurrence of mycotoxins in cereals and cereal-derived food products: public health perspectives of their co-occurrence. J Agric Food Chem 65(33):7034–7051. (PMID: 10.1021/acs.jafc.6b04847) ; Li PW, Zhang DH, Yang Y, Cui YH, Zhang Q, Zhang W (2010) A review of the detoxification of aflatoxins in cereal and oilseeds products. Chin J Oil Crop Sci 32(2):315–319. ; Liu BH, Yu FY, Chan MH, Yang YL (2002) The effects of mycotoxins, fumonisin B 1 and aflatoxin B 1 , on primary swine alveolar macrophages. Toxicol Appl Pharmacol 180(3):197–204. (PMID: 10.1006/taap.2002.9406) ; Long M, Tao S, Rojo de la Vega M, Jiang T, Wen Q, Park SL, Zhang DD, Wondrak GT (2015) Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde. Cancer Prev Res (Phila) 8:444–454. (PMID: 10.1158/1940-6207.CAPR-14-0359) ; Lu ZH, Mu YM, Wang BA, Li XL, Lu JM, Li JY, Pan CY, Yanase T, Nawata H (2003) Saturated free fatty acids, palmitic acid and stearic acid, induce apoptosis by stimulation of ceramide generation in rat testicular Leydig cell. Biochem Biophys Res Commun 303:1002–1007. (PMID: 10.1016/S0006-291X(03)00449-2) ; Malik J, Munjal K, Deshmukh R (2015) Attenuating effect of standardized lyophilized Cinnamomum zeylanicum bark extract against streptozotocin-induced experimental dementia of Alzheimer’s type. J Basic Clin Physiol Pharmacol 26(3):275–285. (PMID: 10.1515/jbcpp-2014-0012) ; Mansour MA, Ginawi OT, El-Hadiyah T, El-Khatib AS, Al-Shabanah OA, Al-Sawaf HA (2001) Effects of volatile oil constituents of Nigella sativa on carbon tetrachloride-induced hepatotoxicity in mice: evidence for antioxidant effects of thymoquinone. Res Commun Mol Pathol Pharmacol 110:239–351. ; Marasas WFO, Kellerman TS, Gelderblom WCA, Coetzer JAW, Thiel PG, Van Der Lugt JJ (1988) Leucoencephalomalacia in a horse induced by fumonisin B 1 isolated from Fusarium moniliforme. Onderstepoort J Vet Res 55:197–203. ; Mary VS, Arias SL, Otaiza SN, Velez PA, Rubinstein HR, Theumer MG (2017) The aflatoxin B 1 and fumonisin B 1 toxicity in BRL-3A hepatocytes is associated to induction of cytochrome P450 activity and arachidonic acid metabolism. Environ Toxicol 32(6):1711–1724. (PMID: 10.1002/tox.22395) ; Mathuria N, Verma RJ (2008) Curcumin ameliorates aflatoxin induced toxicity in mice spermatozoa. Fertil Steril 90(3):775–780. (PMID: 10.1016/j.fertnstert.2007.07.1300) ; Matur E, Ergul E, Akyazi I, Eraslan E, Inal G, Bilgic S, Demircan H (2011) Effects of Saccharomyces cerevisiae extract on haematological parameters, immune function and the antioxidant defense system in breeder hens fed aflatoxin contaminated diets. Br Poult Sci 52:541–550. (PMID: 10.1080/00071668.2011.617726) ; McClements DJ, Rao J (2011) Food-grade nanoemulsions: formulation, fabrication, properties, performance, biological fate, and potential toxicity. Crit Rev Food Sci Nutr 51(4):285–330. (PMID: 10.1080/10408398.2011.559558) ; Merrill AH Jr, Sullards MC, Wang E, Voss KA, Riley RT (2001) Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. Environ Health Perspect 109(2):283–289. ; Milićević D, Nastasijevic I, Petrovic Z (2016) Mycotoxin in the food supply chain-implications for public health program. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 34(4):293–319. (PMID: 10.1080/10590501.2016.1236607) ; Mollazadeh H, Hosseinzadeh H (2016) Cinnamon effects on metabolic syndrome: a review based on its mechanisms. Iran J Basic Med Sci 19(12):1258–1270. ; Mooyottu S, Kollanoor-Johny A, Flock G, Bouillaut L, Upadhyay A, Sonenshein AL, Venkitanarayanan K (2014) Carvacrol and trans-cinnamaldehyde reduce Clostridium difficile toxin production and cytotoxicity in vitro. Int J Mol Sci 15(3):4415–4430. (PMID: 10.3390/ijms15034415) ; Morr CV, Ha EYW (1993) Whey protein concentrates and isolate processing and functional properties. Crit Rev Food Sci Nutr 33:431–476. (PMID: 10.1080/10408399309527643) ; Moselhy SS, Ali HKH (2009) Hepatoprotective effect of cinnamon extracts against carbon tetrachloride induced oxidative stress and liver injury in rats. Biol Res 42:93–98. (PMID: 10.4067/S0716-97602009000100009) ; Moselhy SS, Junbi HH (2010) Antioxidant properties of ethanolic and aqueous Cinnamon extracts against liver injury in rats. Int J Adv Pharm Sci 1(2):151–155. ; Murashiki TC, Chidewe C, Benhura MA, Maringe DT, Dembedza MP, Manema LR, Mvumi BM, Nyanga LK (2017) Levels and daily intake estimates of aflatoxin B 1 and fumonisin B 1 in maize consumed by rural households in Shamva and Makoni districts of Zimbabwe. Food Control 72:105–109. (PMID: 10.1016/j.foodcont.2016.07.040) ; Noori S, Azmat M, Mahboob T (2012) Study on antioxidant effects of cinnamon and garlic extract in liver, kidney and heart tissue of rat. Biosci Res 9(1):17–22. ; Ortatatli M, Ciftci K, Tuzcu M, Kaya A (2002) The effects of aflatoxin on the reproductive system of roosters. Res Vet Sci 72:29–36. (PMID: 10.1053/rvsc.2001.0516) ; Ostry V, Malir F, Toman J, Grosse Y (2017) Mycotoxins as human carcinogens-the IARC monographs classification. Mycotoxin Res 33(1):65–73. (PMID: 10.1007/s12550-016-0265-7) ; Paranagama P, Wimalasena S, Jayatilake GS, Jayawardena AL, Senanayake UM, Mubarak AM (2010) A comparison of essential oil constituents of bark, leaf, root and fruit of cinnamon (Cinnamomum zeylanicum Blum) grown in Sri Lanka. J Natl Sci Found Sri Lanka 29(3–4):147–153. ; Paterson RRM, Lima N (2010) In: Luch A (ed) Toxicology of mycotoxins. Mol. Clin. Environ. Toxicol. Birkhäuser, Basel, pp 31–63. (PMID: 10.1007/978-3-7643-8338-1_2) ; Payne AH, Youngblood GL (1995) Regulation of expression of steroidogenic enzymes in Leydig cells. Biol Reprod 52(2):217–225. (PMID: 10.1095/biolreprod52.2.217) ; Peng X, Xiong YL, Kong B (2009) Antioxidant activity of peptide fractions from whey protein hydrolysates as measured by electron spin resonance. Food Chem 113:196–201. (PMID: 10.1016/j.foodchem.2008.07.068) ; Peng X, Chen K, Chen J, Fang J, Cui H, Zuo Z, Deng J, Chen Z, Geng Y, Lai W, Peng X, Chen K, Chen J, Fang J, Cui H, Zuo Z, Deng J, Chen Z, Geng Y, Lai W (2016) Aflatoxin B 1 affects apoptosis and expression of Bax, Bcl-2, and Caspase-3 in thymus and bursa of fabricius in broiler chickens. Environ Toxicol 31(9):1113–1120. (PMID: 10.1002/tox.22120) ; Perandones CE, Illera VA, Peckham D, Stunz LL, Ashman RF (1993) Regulation of apoptosis in vitro in mature murine spleen T cells. J Immunol 151:3521–3529. ; Pereira VL, Fernandes JO, Cunha SC (2014) Mycotoxins in cereals and related foodstuffs: a review on occurrence and recent methods of analysis. Trends Food Sci Technol 36:96–136. (PMID: 10.1016/j.tifs.2014.01.005) ; Qadir MMF, Bhatti A, Ashraf MU, Sandhu MA, Anjum S, John P (2017) Immunomodulatory and therapeutic role of Cinnamomum verum extracts in collagen-induced arthritic BALB/c mice. Inflammopharmacol 26:157–170. https://doi.org/10.1007/s10787-017-0349-9. (PMID: 10.1007/s10787-017-0349-9) ; Raben N, Nichols RC, Martiniuk F, Plotz PH (1996) A model of mRNA splicing in adult lysosomal storage disease Glycogenosis type II. Hum Mol Genet 5:995–1001. (PMID: 10.1093/hmg/5.7.995) ; Raina VK, Srivastava SK, Aggraval KK, Ramesh S, Kumar S (2001) Essential oil composition of Cinnamon zeylanicum Blume leaves from little Andaman. India Flav Frag J 16:374–376. (PMID: 10.1002/ffj.1016) ; Ramachandran A, Madesh M, Balasubramanian KA (2000) Apoptosis in the intestinal epithelium: its relevance in normal and pathophysiological conditions. J Gastroenterol Hepatol 15:109–120. (PMID: 10.1046/j.1440-1746.2000.02059.x) ; Ranasinghe P, Perera S, Gunatilake M, Abeywardene E, Gunapala N, Premakumara S, Perera K, Lokuhetty D, Katulanda P (2012) Effects of Cinnamomum zeylanicum (Ceylon cinnamon) on blood glucose and lipids in a diabetic and healthy rat model. Pharm Res 4(2):73–79. ; Ranasinghe P, Pigera S, Premakumara GA, Galappaththy P, Constantine GR, Katulanda P (2013) Medicinal properties of ‘true’ cinnamon (Cinnamomum zeylanicum): a systematic review. BMC Complement Altern Med 13(1):275. https://doi.org/10.1186/1472-6882-13-275. (PMID: 10.1186/1472-6882-13-275) ; Rao AJ, Charaborti R, Kotagi SG, Ravindranath N (1990) Effect of constant infusion of gonadotropins releasing hormone GnRH against buserelin and antagonist CDB 2085 A using osmotic mini pumps on testicular function in adult male bonnet monkey (Macaca radiata). Andrologia 22:567–573. (PMID: 10.1111/j.1439-0272.1990.tb02056.x) ; Rawal S, Kim JE, Coulombe JR (2010) Aflatoxin B 1 in poultry: toxicology, metabolism and prevention. Res Vet Sci 89:325–331. (PMID: 10.1016/j.rvsc.2010.04.011) ; Rodrigues I, Naehrer K (2012) A three-year survey on the worldwide occurrence of mycotoxins in feedstuffs and feed. Toxins (Basel) 4:663–675. (PMID: 10.3390/toxins4090663) ; Roger B, Lagarce F, Garcion E, Benoit JP (2010) Biopharmaceutical parameters to consider in order altering the fate of nanocarriers after oral delivery. Nanomedicine 5(2):287–306. (PMID: 10.2217/nnm.09.110) ; Rupa P, Mine Y (2012) Recent advances in the role of probiotics in human inflammation and gut health. J Agric Food Chem 60:8249–8256. (PMID: 10.1021/jf301903t) ; Sambrook J, Russell D (2001) Molecular cloning: a laboratory manual, 3rd edn. Cold Spring Harbor Lab. Press, Cold Spring Harbor. ; Sariözkan S, Türk G, Güvenç M, Yüce A, Özdamar S, Cantürk F, Yay AH (2016) Effects of Cinnamon (C. zeylanicum) Bark oil against taxanes-induced damages in sperm quality, testicular and epididymal oxidant/antioxidant balance, testicular apoptosis, and sperm DNA integrity. Nutr Cancer 68(3):481–494. (PMID: 10.1080/01635581.2016.1152384) ; SAS (1982) Institute Inc. SAS User’s Guide: Statistics. SAS Institute, Cary. ; Schoemaker MH, Ros JE, Homan M, Trautwein C, Liston P, Poelstra K, van Goor H, Jansen PLM, Moshage H (2002) Cytokine regulation of pro- and anti-apoptotic genes in rat hepatocytes: NF-kB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents apoptosis. J Hepatol 36:742–750. (PMID: 10.1016/S0168-8278(02)00063-6) ; Sekher A, Pannala-Chan TS, O’Brien PJ, Rice-Evans CA (2001) Flavonoid B-ring chemistry and antioxidant activity: fast reaction kinetics. Biochem Biophys Res Commun 282:1161–1168. (PMID: 10.1006/bbrc.2001.4705) ; Shihabudeen M, Priscilla H, Thirumurugan K (2011) Cinnamon extract inhibits glucosidase activity and dampens postprandial glucose excursion in diabetic rats. Nutr Metab 8:1–11. (PMID: 10.1186/1743-7075-8-1) ; Singh KB, Maurya BK, Trigun SK (2015) Activation of oxidative stress and inflammatory factors could account for histopathological progression of aflatoxin-B 1 induced hepatocarcinogenesis in rat. Mol Cell Biochem 401(1–2):185–196. (PMID: 10.1007/s11010-014-2306-x) ; Sivakumar JT, Gowder T, Devaraj H (2006) Effect of the food flavour cinnamaldehyde on the antioxidant status of rat kidney. Basic Clin Pharmacol Toxicol 99:379–382. (PMID: 10.1111/j.1742-7843.2006.pto_560.x) ; Stockmann-Juvala H, Savolainen K (2008) A review of the toxic effects and mechanisms of action of fumonisin B 1 . Hum Exp Toxicol 27:799–809. (PMID: 10.1177/0960327108099525) ; Stoev SD (2015) Foodborne mycotoxicoses, risk assessment and underestimated hazard of masked mycotoxins and joint mycotoxin effects or interaction. Environ Toxicol Pharmacol 39(2):794–809. (PMID: 10.1016/j.etap.2015.01.022) ; Streit E, Schatzmayr G, Tassis P, Tzika E, Marin D, Taranu I, Tabuc C, Nicolau A, Aprodu I, Puel O, Oswald IP (2012) Current situation of mycotoxin contamination and co-occurrence in animal feedefocus on Europe. Toxins (Basel) 4:788–809. (PMID: 10.3390/toxins4100788) ; Sun LH, Lei MY, Zhang NY, Gao X, Li C, Krumm CS, Qi DS (2015) Individual and combined cytotoxic effects of aflatoxin B 1 , zearalenone, deoxynivalenol and fumonisin B 1 on BRL 3A rat liver cells. Toxicon 95:6–12. (PMID: 10.1016/j.toxicon.2014.12.010) ; Sun XD, Su P, Shan H (2017) Mycotoxin contamination of rice in. China J Food Sci 82(3):573–584. (PMID: 10.1111/1750-3841.13631) ; Supriya C, Girish BP, Reddy SP (2014) Aflatoxin B 1 -induced reproductive toxicity in male rats: possible mechanism of action. Int J Toxicol 33(3):155–161. (PMID: 10.1177/1091581814530764) ; Szabó-Fodor J, Kachlek M, Cseh S, Somoskői B, Szabó A, Bodnár ZB, Tornyos G, Mézes M, Balogh K, Glávits R, Hafner D, Kovács M (2015) Individual and combined effects of subchronic exposure of three Fusarium toxins (Fumonisin B, Deoxynivalenol and Zearalenone) in rabbit bucks. Clin Toxicol 5:4–15. ; Towner RA, Qian SY, Kadiiska MB, Mason RP (2003) In vivo identification of aflatoxin-induced free radicals in rat bile. Free Radic Biol Med 35:1330–1340. (PMID: 10.1016/j.freeradbiomed.2003.08.002) ; Tran QI, Adnyana IK, Tezuka Y, Nagaoka T, Tran QK, Kadota S (2001) Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocyte protective activity. J Nat Prod 64:456–461. (PMID: 10.1021/np000393f) ; Tseng Y, Lin S, Hsiao J, Chen I, Lee J, Wu S, Tsa L (2006) Whey protein concentrate promotes the production of glutathione (GSH) by GSH reductase in the PC12 cell line after acute ethanol exposure. Food Chem Toxicol 44:574–578. (PMID: 10.1016/j.fct.2005.09.003) ; Tuzcu Z, Orhan C, Sahin N, Juturu V, Sahin K (2017) Cinnamon polyphenol extract inhibits hyperlipidemia and inflammation by modulation of transcription factors in high-fat diet-fed rats. Oxid Med Cell Longev 2017: Article ID 1583098. https://doi.org/10.1155/2017/1583098. ; Udomkun P, Wiredu AN, Nagle M, Bandyopadhyay R, Müller J, Vanlauwe B (2017) Mycotoxins in Sub-Saharan Africa: present situation, socio-economic impact, awareness, and outlook. Food Control 72:110–122. (PMID: 10.1016/j.foodcont.2016.07.039) ; Van Der Hoeven JA, Moshage H, Schuurs T, Nijboer M, Van Schilfgaarde R, Ploeg RJ (2003) Brain death induces apoptosis in donor liver of the rat. Transplantation 76(8):1150–1154. (PMID: 10.1097/01.TP.0000080983.14161.95) ; Verheecke C, Liboz T, Mathieu F (2016) Microbial degradation of aflatoxin B1: current status and future advances. Int J Food Microbiol 237:1–9. (PMID: 10.1016/j.ijfoodmicro.2016.07.028) ; Verma RJ, Nair A (2002) Effect of aflatoxins on testicular steroidogenesis and amelioration by vitamin E. Food Chem Toxicol 40:669–672. (PMID: 10.1016/S0278-6915(01)00131-4) ; Vijayan P, Prashanth HC, Dhanraj SA, Badami S, Suresh B (2003) Hepatoprotective effect of total alkaloid fraction of Solanum pseudocapsicum leaves. Pharm Biol 41:443–448. (PMID: 10.1076/phbi.41.6.443.17827) ; Voss KA, Riley RT, Gelineauvan WJ (2014) Fumonisin B1 induced neural tube defects were not increased in LM/Bc mice fed folate-deficient diet. Mol Nutr Food Res 58:1190–1198. (PMID: 10.1002/mnfr.201300720) ; Wagacha JM, Muthomi JW (2008) Mycotoxin problem in Africa: current status, implications to food safety and health and possible management strategies. Int J Food Microbiol 124:1–12. (PMID: 10.1016/j.ijfoodmicro.2008.01.008) ; Waller RA, Duncan DB (1969) A Bayes rule for the symmetric multiple comparison problems. J Am Stat Assoc 64:1484–1503. ; Wang HF, Wang YK, Yih KH (2007) DPPH free-radical scavenging ability, total phenolic content, and chemical composition analysis of forty-five kinds of essential oils. J Cosmet Sci 59(6):509–522. ; Wang R, Wang R, Yang B (2009) Extraction of essential oils from five cinnamon leaves and identification of their volatile compound compositions. Innovative Food Sci Emerg Technol 10:289–292. (PMID: 10.1016/j.ifset.2008.12.002) ; WHO (1998) Forty-ninth report of the joint FAO/WHO expert committee on food additives. WHO Technical Report Series. WHO, Geneva. ; Wiame I, Remy S, Swennen R, Sagi L (2000) Irreversible heat inactivation of DNaseI without RNA degradation. Biotechniques 29:252–256. (PMID: 10.2144/00292bm11) ; Wu F, Groopman JD, Pestka JJ (2014) Public health impacts of foodborne mycotoxins. Annu Rev Food Sci Technol 5:351–372. (PMID: 10.1146/annurev-food-030713-092431) ; Wu C, Zhuang Y, Jiang S, Tian F, Teng Y, Chen X, Zheng P, Liu S, Zhou J, Wu J, Wang R, Zou X (2017) Cinnamaldehyde induces apoptosis and reverses epithelial-mesenchymal transition through inhibition of Wnt/β-catenin pathway in non-small cell lung cancer. Int J Biochem Cell Biol 84:58–74. (PMID: 10.1016/j.biocel.2017.01.005) ; Xing Y, Li X, Xu Q, Yun J, Lu Y, Tang Y (2011) Effects of chitosan coating enriched with cinnamon oil on qualitative properties of sweet pepper Capsicum annuum L. Food Chem 124:1443–1450. (PMID: 10.1016/j.foodchem.2010.07.105) ; Xiong X, Chen W, Cui J, Yi S, Zhang Z, Li K (2003) Effects of ursolic acid on liver protection and bile secretion. Zhong Yao Cai 26:578–581. ; Yang J, Bai F, Zhang K, Bai S, Peng X, Ding X, Li Y, Zhang J, Zhao L (2012) Effects of feeding corn naturally contaminated with aflatoxin B 1 and B 2 on hepatic functions of broilers. Poult Sci 91:2792–2801. (PMID: 10.3382/ps.2012-02544) ; Yuan HD, Huang B, Chung SH (2011) Protective effect of cinnamaldehyde on streptozotocin-induced damage in rat pancreatic b-cells. Food Sci Biotechnol 20(5):1271–1276. (PMID: 10.1007/s10068-011-0175-6) ; Yüce A, Türk G, Çeribaşi S, Sönmez M, Çiftçi M, Güvenç M (2013) Effects of cinnamon (Cinnamomum zeylanicum) bark oil on testicular antioxidant values, apoptotic germ cell and sperm quality. Andrologia 45(4):248–255. (PMID: 10.1111/and.12000) ; Yunus AW, Razzazi-Fazeli E, Bohm J (2011) Aflatoxin B 1 in affecting broiler’s performance, immunity, and gastrointestinal tract: a review of history and contemporary issues. Toxins (Basel) 3:566–590. (PMID: 10.3390/toxins3060566)
- Grant Information: 11090341 and 1070112 National Research Centre
- Contributed Indexing: Keywords: Aflatoxin B1; Cinnamon oil; Cytotoxicity; Encapsulation; Fumonisin B1; Mycotoxins
- Substance Nomenclature: 0 (Fumonisins) ; 0 (Oils, Volatile) ; 0 (Plant Oils) ; 0 (Protective Agents) ; 0 (Whey Proteins) ; 3ZZM97XZ32 (fumonisin B1) ; 9N2N2Y55MH (Aflatoxin B1)
- Entry Date(s): Date Created: 20180817 Date Completed: 20190121 Latest Revision: 20210224
- Update Code: 20231215
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