[Inflammasome--essential regulator of the inflammatory reaction].
In: Duodecim; laaketieteellinen aikakauskirja, Jg. 129 (2013), Heft 7, S. 705-11
academicJournal
Zugriff:
The function of inflammasome in the cell is to sense intracellular danger signals and--perhaps as the last cry of distress of a cell invaded by a microorganism--at an emergency situation to release interleukins (IL) outside of the cell, causing an inflammatory reaction and fever and also leads to an elevation of CRP. In a hopeless situation inflammasome-regulated pyroptosis is started. Disturbed action of inflammasomes has been linked to the pathogenesis of various disorders such as gout, atherosclerosis, asbestosis and type 2 diabetes. As the pathogenetic mechanisms of such diseases become clear, improved treatments for them may also become available.
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[Inflammasome--essential regulator of the inflammatory reaction].
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Autor/in / Beteiligte Person: | Junttila, I ; Meri, S ; Rämet, M |
Zeitschrift: | Duodecim; laaketieteellinen aikakauskirja, Jg. 129 (2013), Heft 7, S. 705-11 |
Veröffentlichung: | Helsinki : Laaeketieteellinen Aikakauskirja Duodecim ; <i>Original Publication</i>: Helsinki, Suomalainen Lääkäriseura Duodecim., 2013 |
Medientyp: | academicJournal |
ISSN: | 0012-7183 (print) |
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