Composition and biological activity of essential oil of Achillea ligustica All. (Asteraceae) naturalized in central Italy: ideal candidate for anti-cariogenic formulations.

Maggi, F ; Bramucci, M ; et al.

In: Fitoterapia, Jg. 80 (2009-09-01), Heft 6, S. 313-9

academicJournal

Essential oil from flowers (FL) and vegetative parts (VP) of Achillea ligustica (Asteraceae), naturalized after cultivation in central Italy, was investigated by GC-FID and GC-MS. The most abundant components were linalool, viridiflorol, beta-pinene, 1,8-cineole and terpinen-4-ol. The antioxidant assays (DPPH and ABTS radical scavenging assays, and beta-carotene bleaching test) demonstrated a moderate activity of essential oils. The antimicrobial activity was evaluated by the broth micro-dilution method on 6 microbial strains and showed to be quite strong against the cariogenic Gram-positive Streptococcus mutans, suggesting that this essential oil could be a valid candidate for anti-cariogenic formulations. Moderate cytotoxic activity was observed in assays on four tumour cell lines by MTT assay.

Titel:	Composition and biological activity of essential oil of Achillea ligustica All. (Asteraceae) naturalized in central Italy: ideal candidate for anti-cariogenic formulations.
Autor/in / Beteiligte Person:	Maggi, F ; Bramucci, M ; Cecchini, C ; Coman, MM ; Cresci, A ; Cristalli, G ; Lupidi, G ; Papa, F ; Quassinti, L ; Sagratini, G ; Vittori, S
Zeitschrift:	Fitoterapia, Jg. 80 (2009-09-01), Heft 6, S. 313-9
Veröffentlichung:	1999- : [Amsterdam] : Elsevier ; <i>Original Publication</i>: Milano : Inverni & Della Beffa S.p.A., 2009
Medientyp:	academicJournal
ISSN:	1873-6971 (electronic)
DOI:	10.1016/j.fitote.2009.04.004
Schlagwort:	Anti-Bacterial Agents isolation & purification Anti-Bacterial Agents therapeutic use Antineoplastic Agents, Phytogenic isolation & purification Antineoplastic Agents, Phytogenic therapeutic use Antioxidants isolation & purification Antioxidants therapeutic use Benzothiazoles Biphenyl Compounds Cell Line, Tumor Dental Caries drug therapy Flowers Humans Italy Oils, Volatile chemistry Oils, Volatile therapeutic use Picrates Plant Oils chemistry Plant Oils therapeutic use Plant Structures Streptococcus mutans drug effects Sulfonic Acids Thiazoles Achillea chemistry Anti-Bacterial Agents pharmacology Antineoplastic Agents, Phytogenic pharmacology Antioxidants pharmacology Oils, Volatile pharmacology Phytotherapy Plant Oils pharmacology
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Research Support, Non-U.S. Gov't Language: English [Fitoterapia] 2009 Sep; Vol. 80 (6), pp. 313-9. <i>Date of Electronic Publication: </i>2009 Apr 17. MeSH Terms: Phytotherapy* ; Achillea / chemistry ; Anti-Bacterial Agents / pharmacology ; Antineoplastic Agents, Phytogenic / pharmacology ; Antioxidants / pharmacology ; Oils, Volatile / pharmacology ; Plant Oils / pharmacology ; Anti-Bacterial Agents / isolation & purification ; Anti-Bacterial Agents / therapeutic use ; Antineoplastic Agents, Phytogenic / isolation & purification ; Antineoplastic Agents, Phytogenic / therapeutic use ; Antioxidants / isolation & purification ; Antioxidants / therapeutic use ; Benzothiazoles ; Biphenyl Compounds ; Cell Line, Tumor ; Dental Caries / drug therapy ; Flowers ; Humans ; Italy ; Oils, Volatile / chemistry ; Oils, Volatile / therapeutic use ; Picrates ; Plant Oils / chemistry ; Plant Oils / therapeutic use ; Plant Structures ; Streptococcus mutans / drug effects ; Sulfonic Acids ; Thiazoles Substance Nomenclature: 0 (Anti-Bacterial Agents) ; 0 (Antineoplastic Agents, Phytogenic) ; 0 (Antioxidants) ; 0 (Benzothiazoles) ; 0 (Biphenyl Compounds) ; 0 (Oils, Volatile) ; 0 (Picrates) ; 0 (Plant Oils) ; 0 (Sulfonic Acids) ; 0 (Thiazoles) ; 28752-68-3 (2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid) ; DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl) Entry Date(s): Date Created: 20090422 Date Completed: 20091105 Latest Revision: 20161125 Update Code: 20240513

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