Age and target organ damage in essential hypertension: role of the metabolic syndrome.
In: American journal of hypertension, Jg. 20 (2007-03-01), Heft 3, S. 296-303
academicJournal
Zugriff:
Objective: We sought to investigate the association of the metabolic syndrome (MS) with cardiovascular alterations in essential hypertensives in relation to age.
Methods: A total of 3266 untreated and treated hypertensive patients categorized in three age groups (I: 17 to 40 years; II: 41 to 64 years; III: >64 years) were considered for this analysis. All patients underwent extensive investigations searching for target organ damage (TOD). The MS was defined according to Advanced Technology Laboratories (ATP) III criteria.
Conclusions: In hypertensive patients the MS amplifies TOD regardless of patient's age, thus increasing cardiovascular risk. This synergistic effect may accelerate the early development of TOD in young hypertensives and enhance the age-associated cardiovascular alterations in the elderly.
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Age and target organ damage in essential hypertension: role of the metabolic syndrome.
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Autor/in / Beteiligte Person: | Cuspidi, C ; Meani, S ; Valerio, C ; Sala, C ; Fusi, V ; Zanchetti, A ; Mancia, G |
Zeitschrift: | American journal of hypertension, Jg. 20 (2007-03-01), Heft 3, S. 296-303 |
Veröffentlichung: | 2013- : Oxford : Oxford University Press ; <i>Original Publication</i>: [New York, NY] : Elsevier, [c1988-, 2007 |
Medientyp: | academicJournal |
ISSN: | 0895-7061 (print) |
DOI: | 10.1016/j.amjhyper.2006.09.010 |
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