[Abnormal glycemic metabolism in essential hypertension. Role of the an oral glucose tolerance test].
In: Medicina clinica, Jg. 125 (2005-07-02), Heft 5, S. 179-81
academicJournal
Zugriff:
Background and Objective: There is a high prevalence of diabetes in essential hypertensive patients, hence increasing the cardiovascular risk of these subjects. Our aim was to test the importance of a routine assessment of an oral glucose tolerance test (OGTT) in a sample of recently diagnosed essential hypertensives.
Patients and Method: We studied 270 recently diagnosed untreated hypertensives (56% males). We measured fasting lipids and plasma glucose and insulin at baseline and after OGTT.
Results: 38.5% of the studied subjects had any abnormality of glucose metabolism, glucose intolerance (22.2%) and type 2 diabetes (12.2%) being the most common. An impaired fasting glucose was present in 4.1% of subjects. Patients with intolerance or type 2 diabetes had a worse plasma lipid profile, and those with impaired fasting glucose, a higher HOMA index.
Conclusions: The high incidence of glucidic abnormalities found in hypertensive patients signals a need to perform an OGTT test in them. This can lead to the implementation of strategies aimed at halting vascular impairment in hypertensives with type 2 diabetes and delay the development of type 2 diabetes in patients with glucose intolerance.
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[Abnormal glycemic metabolism in essential hypertension. Role of the an oral glucose tolerance test].
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Autor/in / Beteiligte Person: | Stiefel, P ; Miranda, ML ; Muñiz, O ; Nieto, MD ; Jiménez, L ; Villar, J |
Zeitschrift: | Medicina clinica, Jg. 125 (2005-07-02), Heft 5, S. 179-81 |
Veröffentlichung: | <2009- > : Madrid : Elsevier España ; <i>Original Publication</i>: Barcelona : Ediciones Doyma, S.A., 2005 |
Medientyp: | academicJournal |
ISSN: | 0025-7753 (print) |
DOI: | 10.1157/13077141 |
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