Chemical Composition, Cytotoxic and Antibacterial Activity of Essential Oil from Aerial Parts of Salvia tebesana Bunge.
In: Journal of Essential Oil-Bearing Plants, Jg. 24 (2021-02-01), Heft 1, S. 31-39
academicJournal
Zugriff:
In the present study, chemical composition, antibacterial and cytotoxic activities of the essential oil (EO) from aerial parts of Salvia tebesana were investigated. Fifty-five compounds representing 99.7 % of the total oil composition were identified using gas chromatography-mass spectrometry analysis. The EO was predominated by oxygenated sesquiterpenes and the main constituents were E-nerolidol, α-eudesmol, trans-caryophyllene, caryophyllene oxide, α-pinene, α-epi-cadinol, δ-cadinene, and β-eudesmol, respectively. The cytotoxic effect of the EO on human breast adenocarcinoma, prostate, and melanoma cancer cell lines were examined using AlamarBlue® assay. The EO indicated significant cytotoxic activity against the tested cell lines particularly PC-3. Moreover, the antibacterial evaluation of EO against four bacterial strains indicated a potent activity against Gram-positive bacteria particularly Staphylococcus aureus (minimum inhibitory concentration: 1.4 μg/mL). [ABSTRACT FROM AUTHOR]
| Titel: |
Chemical Composition, Cytotoxic and Antibacterial Activity of Essential Oil from Aerial Parts of Salvia tebesana Bunge.
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| Autor/in / Beteiligte Person: | Asili, Javad ; Tayarani-Najaran, Zahra ; Emami, Seyed Ahmad ; Iranshahi, Mehrdad ; Sahebkar, Amirhossein ; Eghbali, Samira |
| Zeitschrift: | Journal of Essential Oil-Bearing Plants, Jg. 24 (2021-02-01), Heft 1, S. 31-39 |
| Veröffentlichung: | 2021 |
| Medientyp: | academicJournal |
| ISSN: | 0972-060X (print) |
| DOI: | 10.1080/0972060X.2021.1886996 |
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