Suppression of neutrophil recruitment in mice by geranium essential oil.
In: Mediators of Inflammation, Jg. 13 (2004-02-01), Heft 1, S. 21-24
Online
academicJournal
Zugriff:
Background : In aromatherapy, essential oils are used as anti-inflammatory remedies, but experimental studies on their action mechanisms are very limited. Aims of the study : To assess their anti-inflammatory activities, the effects of essential oils on neutrophil recruitment in mice were examined in vivo . Method : The effect of essential oils on leukocyte and neutrophil recruitment induced 6 h after intraperitoneal injection of casein in mice was examined. Results : Leukocyte recruitment into the peritoneal cavity in mice was suppressed by intraperitoneal injections of geranium, lemongrass and spearmint oils at the dose of 5 μl/mouse, but was not by tea tree oil. This recruitment was inhibited dose-dependently by geranium oil. The suppression of leukocyte recruitment resulted from inhibition of neutrophil accumulation. Conclusion : Some essential oils used as anti-inflammatory remedies suppress neutrophil recruitment into the peritoneal cavity in mice. [ABSTRACT FROM AUTHOR]
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Suppression of neutrophil recruitment in mice by geranium essential oil.
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Autor/in / Beteiligte Person: | Abe, Shigeru ; Maruyama, Naho ; Hayama, Kazumi ; Inouye, Shigeharu ; Oshima, Haruyuki ; Yamaguchi, Hideyo |
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Zeitschrift: | Mediators of Inflammation, Jg. 13 (2004-02-01), Heft 1, S. 21-24 |
Veröffentlichung: | 2004 |
Medientyp: | academicJournal |
ISSN: | 0962-9351 (print) |
DOI: | 10.1080/09629350410001664798 |
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