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Effects of Oregano Essential Oil on IgA + , IgG + , and IgM + Cells in the Jejunum of Castrated Holstein Bulls.
In: Animals (2076-2615), Jg. 13 (2023-12-15), Heft 24, S. 3766-3780
Online
academicJournal
Zugriff:
Simple Summary: Oregano essential oil is a volatile essential oil that plays an important regulatory role in various species, but whether it has an immune-boosting effect on castrated Holstein bulls has not been reported to date. Thus, the effects of oregano essential oil on IgA+, IgG+, and IgM+ cells in the jejuna of castrated Holstein bulls were studied. The results show that the addition of the oil did not change the diffuse distribution of IgA+, IgG+, and IgM+ cells, but repaired damaged intestinal epithelium, inhibited inflammation, and reduced the content of IgA+, IgG+ and IgM+ cells in the jejunum. This provides strong evidence for further research on the mechanism by which oregano essential oil improves the production performance of castrated Holstein bulls. The aim of this study was to investigate the effect of oregano essential oil on IgA+, IgG+, and IgM+ cells in the jejunum of castrated Holstein bulls. Twelve castrated Holstein bulls were randomly divided into control (YCK) and oregano essential oil (YEO) groups. Pathological changes in the jejunum were observed by HE staining, and the expression levels of IgA, IgG, and IgM in the jejunum were detected by ELISA. The distributions of IgA+, IgG+, and IgM+ cells in the jejunum were analysed by multiplex immunofluorescence and immunohistochemistry. The results showed that the jejunal villi were detached in the YCK group, which may have been related to inflammation, while the intestinal epithelium was clear and intact in the YEO group. The expressions of IgA, IgG, and IgM were significantly reduced by 40.75%, 30.76%, and 50.87%. The IgA+, IgG+, and IgM+ cells were diffusely distributed in the lamina propria of the jejunum, and were reduced by 17.07%, 6.44%, and 6.15%, respectively. Oregano essential oil did not alter the distribution characteristics of IgA+, IgG+, or IgM+ cells in the jejunum, but it suppressed inflammatory response, decreased immunoglobulin content, and significantly enhanced the formation of an immune barrier in the gastrointestinal mucosa. [ABSTRACT FROM AUTHOR]
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Effects of Oregano Essential Oil on IgA + , IgG + , and IgM + Cells in the Jejunum of Castrated Holstein Bulls.
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Autor/in / Beteiligte Person: | Liu, Qiyan ; Zhang, Wangdong ; Wang, Baoshan ; Shi, Jinping ; He, Pengjia ; Jia, Li ; Huang, Yongliang ; Xu, Meiling ; Ma, Yue ; Cheng, Qiang ; Lei, Zhaomin |
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Zeitschrift: | Animals (2076-2615), Jg. 13 (2023-12-15), Heft 24, S. 3766-3780 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 2076-2615 (print) |
DOI: | 10.3390/ani13243766 |
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