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Essential oil composition and biological activities of Aleppo pine (Pinus halepensis Miller) needles collected from different Tunisian regions.
In: International Journal of Environmental Health Research, Jg. 33 (2023), Heft 1, S. 83-97
Online
academicJournal
Zugriff:
The aim of this research was to investigate the variation regarding the chemical composition and biological activities of needles essential oils (EOs) of P. halepensis. Chemical profiles demonstrated a significant (P < 0.05) variability among the different EOs. The main identified compounds were caryophyllene (48.77 ± 2.26), phenyl isovalerate (22.22 ± 2.26), β-myrcene (15.55 ± 5.65) and α-pinene (14.52 ± 2.26). Further, it was shown that EO from Tabouba (Tab) displayed the highest DPPH scavenging (IC50 = 73.03 mg/mL), anti-inflammatory (IC50 = 23.29 µg/mL) and α-glucosidase inhibition activities (IC50 = 254.45 µg/mL). While Elmahres (Elm) exhibited the most potent ABTS radical's inhibition (IC50 = 197.87 mg/mL). For the cytotoxic capacities, Kettana (Ket) was the most efficient against breast cancer MCF-7 cell line with IC50 value better than doxorubicin used as positive control. Obtained results suggest that EO of P. halepensis could be used as a source of bioactive compounds. [ABSTRACT FROM AUTHOR]
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Essential oil composition and biological activities of Aleppo pine (Pinus halepensis Miller) needles collected from different Tunisian regions.
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Autor/in / Beteiligte Person: | Dakhlaoui, Sarra ; Bourgou, Soumaya ; Bachkouel, Sarra ; Ben Mansour, Rim ; Ben Jemaa, Mariem ; Jallouli, Slim ; Megdiche-Ksouri, Wided ; Hessini, Kamel ; Msaada, Kamel |
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Zeitschrift: | International Journal of Environmental Health Research, Jg. 33 (2023), Heft 1, S. 83-97 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 0960-3123 (print) |
DOI: | 10.1080/09603123.2021.2005001 |
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